Results 91 to 100 of about 58,334 (260)
Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib
The antitumorigenic mechanism of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib is still a matter of debate. Among different structurally related COX-2 inhibitors, only celecoxib was found to cause apoptosis and cell death of human lung ...
Robert Ramer +5 more
doaj +1 more source
Multicentre observational cohort study of NSAIDs as risk factors for postoperative adverse events in gastrointestinal surgery [PDF]
Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as postoperative analgesia by the Enhanced Recovery After Surgery Society. Recent studies have raised concerns that NSAID administration following colorectal anastomosis may be ...
Bhangu, A +6 more
core +1 more source
Abstract Background Previous observational studies have reported an increased risk of venous thromboembolism (VTE) among non‐steroidal anti‐inflammatory drug (NSAID) users compared with non‐users. However, these studies may have been subject to bias due to unmeasured confounders related to patient conditions requiring NSAIDs.
Yuichiro Matsuo +2 more
wiley +1 more source
Background. Arthritis is a common condition that co-exists in the elderly population. This condition leads to frequent administration of comorbid analgesics especially non steroidal anti-inflammatory drugs (NSAIDs). Aim.
Ragia Hegazy +2 more
doaj +1 more source
Background: Celecoxib is a non-steroidal anti-inflammatory drug used extensively in the treatment of pain, arthritis, and cancers. However, its administration is limited due to its several disadvantages including gastric irritation and hepatic first pass
Sepideh Mardani 1, Maryam Maghsoodi 2 * , Saeed Ghanbarzadeh 3,4, Ali Nokhodchi 5, Shadi Yaqoubi 6, Hamed Hamishehkar 7 *
doaj +1 more source
Celecoxib Derivatives Containing Pyrazole Linked‐Sulfonamide Moiety: Carbonic Anhydrase I–II and Acetylcholinesterase Inhibition Profiles, Molecular Docking Studies [PDF]
Serpil Gerni +4 more
openalex +1 more source
Postoperative Prescription Patterns After Sleep Surgery: An International Provider Survey Study
ABSTRACT Objective To characterize international opioid prescribing patterns among otolaryngologists performing sleep surgery. Methods Cross‐sectional online survey of otolaryngologists and health care professionals who are members of the International Sleep Surgical Society (ISSS).
Amrita N. Bhat +3 more
wiley +1 more source
Effects of Cetuximab Combined with Celecoxib on Apoptosis and KDR and AQP1 Expression in Lung Cancer
Background and objective Neoadjuvant chemotherapy is a new development in the treatment of lung cancer. In recent years, cetuximab and celecoxib have been commonly used in this procedure.
Honggang XIA +3 more
doaj +1 more source
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
A bench‐stable boryl thianthrenium dication is synthesized via thianthrenation of vinyl MIDA boronate. This novel dication enables metal‐free, chemo‐, and diastereoselective late‐stage aziridination with diverse nitrogen nucleophiles. The strategic significance is further showcased by one‐pot electrochemical and asymmetric protocols and versatile ...
Veerabhadra R. Vulupala +7 more
wiley +2 more sources

