Results 111 to 120 of about 58,334 (260)

Bifunctional Aziridines from Photochemically Generated FSO2NH2 for SuFEx Diversification of Alkenes

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Photochemically generated FSO2NH2 serves as a safe, practical nitrene precursor for Rh‐catalyzed aziridination of alkenes, granting access to previously inaccessible fluorosulfonyl aziridines. These bifunctional electrophiles merge aziridine ring strain with SuFEx reactivity to provide a modular platform toward aliphatic sulfamoyl fluoride derivatives ...
Avinash Choudhury, Varun Prabhakar, Zakary B. Newman, Quentin Michaudel   +3 more
wiley   +2 more sources

Antinflamatorios no esteroideos y seguridad cardiovascular: ¿es naproxeno más seguro que celecoxib? Nuevas evidencias [PDF]

, 2017
A. Alcántara-Montero, A. González-Curado   +1 more
openalex   +1 more source

Safety of celecoxib versus traditional nonsteroidal anti-inflammatory drugs in older patients with arthritis

Journal of Pain Research, 2018
Sooyoung Shin1,2 1Department of Clinical Pharmacy, College of Pharmacy, Ajou University, Yeongtong-gu, Suwon, Republic of Korea; 2Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Yeongtong-gu, Suwon, Republic of Korea
Shin S
doaj  

Celecoxib and rofecoxib have different effects on small intestinal ischemia/reperfusion injury in rats

Frontiers in Pharmacology
IntroductionIntestinal ischemia/reperfusion (I/R) injury is associated with high mortality and there is an unmet need for novel therapies. The intestinal expression of cyclooxygenase-2 (COX-2) increases rapidly after mesenteric I/R, but it is still a ...
Szilvia B. László, Barbara Hutka, Barbara Hutka, András S. Tóth, András S. Tóth, Tamás Hegyes, Zsuzsanna O. Demeter, Zsuzsanna O. Demeter, Arezoo Haghighi, Arezoo Haghighi, Gerda Wachtl, Gerda Wachtl, Ágnes Kelemen, Anna Jakab, Klára Gyires, Klára Gyires, Zoltán S. Zádori, Zoltán S. Zádori   +17 more
doaj   +1 more source

Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression.

PLoS ONE, 2019
The current study aimed to identify the radiosensitizing effect of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in combination with radiotherapy in non-small-cell lung cancer (NSCLC) cells. The combination of celecoxib potentiated radiation-
Pan Zhang, Dan He, Erqun Song, Mingdong Jiang, Yang Song   +4 more
doaj   +1 more source

Efavirenz and CYP2C9 Genetic Polymorphisms Reduce CYP2C9 Activity in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Efavirenz's effects on cytochrome P450 2C9 (CYP2C9) activity have not been formally characterized in vivo. We conducted the first clinical drug–drug interaction (DDI) study to test the effect of chronic efavirenz dosing on CYP2C9 activity, using tolbutamide as a selective probe.
Jason D. Kim, Ingrid F. Metzger, Jessica Bo Li Lu, Todd C. Skaar, Zeruesenay Desta   +4 more
wiley   +1 more source

Prescribing patterns of celecoxib and prescribers′ perceptions among three general hospitals in Northern Malaysia

Archives of Pharmacy Practice, 2014
Objectives: This paper describes the clinical use of celecoxib in three major, government-subsidized hospitals across Northern Malaysia. Doctors′ perceptions of issues related to celecoxib and other nonsteroidal anti-inflammatory drugs (NSAIDs) were ...
Huan-Keat Chan, Ema Bakri, Sing-Yi Tan, Mohamed Azmi Hassali, Fahad Saleem, Tahir Mehmood Khan   +5 more
doaj   +1 more source

GPNMB immunohistochemistry is a useful ancillary tool for the diagnosis of pulmonary lymphangioleiomyomatosis

Histopathology, Volume 88, Issue 3, Page 698-709, February 2026.
We evaluated the diagnostic utility of GPNMB immunohistochemistry in LAM. GPNMB showed strong expression in LAM cells, while the differential diagnostic mimics showed no or only low expression. Based on its 100% sensitivity and specificity in our cohort, GPNMB is a highly reliable immunohistochemical marker for the diagnosis of LAM.
Fatime Szalai, Judit Pápay, Katalin Dezső, Levente Kuthi, Anna Sebestyén, András Khoór, Ildikó Krencz   +6 more
wiley   +1 more source

Augmented cytotoxic, mutagenic and genotoxic response triggered by carvedilol and celecoxib combinations [PDF]

, 2018
Ali Attiq, Muhammad Ashraf, Juriyati Jalil, Aqeel Javeed, Aftab Ahmad Anjum, Asad Ullah, Muhammad Umair, Sarwat Ali   +7 more
openalex   +1 more source

The dual role of CCND1 in heterotopic ossification: A Non-canonical Pathway for Celecoxib treatment

Heliyon
Objective: To explore the effective targets of Celecoxib in the treatment of heterotopic ossification using network pharmacology methods. Methods: Potential molecules related to heterotopic ossification were obtained by retrieving the GEO and CTD ...
Wei Liu, Junchao Huang, Jianhai Hu, Ziheng Bu, Zheng Zhou, Jianing Yu, Huajun Wang, Xinbo Wu, Peng Wu   +8 more
doaj   +1 more source