Results 111 to 120 of about 50,777 (219)

Celecoxib

Revista de Medicina de la Universidad de Navarra, 2017
E, Caballero, E, Cárdenas, A, Rodrigo, N, Gurucharri, J, Honorato   +4 more
openaire   +3 more sources

In Silico and In Vitro Therapeutic Effects of Phycocyanin Against Lipid Micelle and/or Endotoxin‐Induced Oxidative Damage and Barrier Dysfunction in Human Intestinal Epithelial Cells Model

Molecular Nutrition &Food Research, Volume 70, Issue 6, 29 March 2026.
PHY was evaluated for its protective effects against oxidative stress, inflammation, and barrier disruption induced by LM and LPS in Caco‐2 cells. PHY improved cell viability, reduced oxidative and inflammatory responses, preserved tight junction integrity, and alleviated ER stress.
Fatma Arrari, Imen Hammami, Mohamed‐Amine Jabri, Hichem Sebai   +3 more
wiley   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Preoperative celecoxib use does not increase risk of myocardial infarction and may be protective against thromboembolic complications following total joint arthroplasty

Journal of Orthopaedic Reports
Purpose: The purpose of this study was to determine if preoperative celecoxib treatment raises the risk of postoperative 1) myocardial infarctions, 2) thromboembolic complications, 3) acute kidney injuries, 4) transfusions, and 5) readmissions. Materials
Matthew L. Magruder, Shabnam Parsa, Ariel N. Rodriguez, Mitchell Ng, Che Hang Jason Wong   +4 more
doaj   +1 more source

Dual Inhibition of COX‐2/5‐LOX Through Novel Hybrids of NSAIDs and Peptides: Insights from Molecular Dynamics Simulation and Per‐Residue Decomposition

ChemistryOpen, Volume 15, Issue 3, March 2026.
Hybrid NSAID–aminoacid molecules have demonstrated excellent activity in inhibiting the cyclooxygenase/lipoxygenase system. Accordingly, the present study describes the synthesis of molecules of this kind, examining their behavior via docking, molecular dynamics simulations and per‐residue energy decomposition analyses.
J. Carlos Jiménez‐Cruz, Ramón Guzmán‐Mejía, Pedro Navarro‐Santos, Hugo A. García‐Gutiérrez, Julio C. Ontiveros‐Rodríguez, Rafael Herrera‐Bucio, Verónica Cortés‐Muñoz, Judit A. Aviña‐Verduzco   +7 more
wiley   +1 more source

The Cost-effectiveness of Celecoxib versus Non-steroidal Anti-inflammatory Drugs plus Proton-pump Inhibitors for Treating Osteoarthritis in Algeria

Journal of Health Economics and Outcomes Research, 2013
# Background Cyclooxygenase-2 inhibitors such as celecoxib are as effective as non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs) in the treatment of osteoarthritis (OA), have fewer gastrointestinal side effects, but are more expensive ...
Nadir Hammoumraoui, Sid Ahmed Kherraf, Joaquin Mould-Quevedo, Tarek A. Ismail   +3 more
doaj  

Neuromuscular exercise in addition to celecoxib versus celecoxib alone for symptomatic and radiographic knee osteoarthritis: a randomized controlled trial

BMC Sports Science, Medicine and Rehabilitation
Background Neuromuscular exercise (NEXA) and celecoxib each are effective for treating knee osteoarthritis (OA), but the potential benefits of combination therapy remain unclear. The aim of this study was to investigate the effects of NEXA in addition to
Xiaotian Yang, Haixin Song, Xuqing Li, Tao Wu, Jianhua Li, Chengqi He   +5 more
doaj   +1 more source

Wound infiltration with local anesthetics during cesarean delivery with intrathecal opioids: A systematic review and meta‐analysis of randomized control trials

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Objective To evaluate the effect on maternal pain of local anesthetic wound infiltration for intra‐cesarean delivery analgesia in patients who also received intrathecal opioids Data sources Scopus, PubMed, and Cochrane Central Register of Controlled Trials were searched from the inception of each database to August 2023.
Valentina Frusone, Kavisha Khanuja, Jacqueline Sinnott, Valentina Bellussi, Guillaume Ducarme, Manuel Gomez‐Rios, Jerome Rosetti, Amanda Roman, Vincenzo Berghella   +8 more
wiley   +1 more source

Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo

Drug Design, Development and Therapy, 2018
Jiayang He,1 Ping Fang,2 Xiang Zheng,2 Chenchen Wang,2 Tenghui Liu,2 Bowen Zhang,2 Jian Wen,2 Ren-ai Xu3 1Department of Pharmacy, The First Hospital of Jiaxing, Jiaxing, Zhejiang, China; 2Department of Pharmacology, School of Pharmacy of Wenzhou Medical
He JY, Fang P, Zheng X, Wang CC, Liu TH, Zhang BW, Wen J, Xu RA   +7 more
doaj  

Adjunctive use of celecoxib with anti-tuberculosis drugs: evaluation in a whole-blood bactericidal activity model

Scientific Reports, 2018
COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response.
Claire M. Naftalin, Rupangi Verma, Meera Gurumurthy, Kim Hor Hee, Qingshu Lu, Benjamin Chaik Meng Yeo, Kin Hup Tan, Wenwei Lin, Buduo Yu, Kok Yong Seng, Lawrence Soon-U Lee, Nicholas I. Paton   +11 more
doaj   +1 more source