Results 51 to 60 of about 58,334 (260)

Meloxicam decreases the migration and invasion of CF41.Mg canine mammary carcinoma cells [PDF]

, 2017
Indexación: Web of Science; Scopus.Cyclooxygenase (COX)-2 expression is positively correlated with malignant features in canine mammary carcinomas. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit COX activity and may therefore possess anticancer ...
Arias, J.I., Iturriaga, M.P., Paredes, R., Torres, C.G.   +3 more
core   +1 more source

Understanding the NSAID related risk of vascular events [PDF]

, 2006
Concern is growing about an increased risk of thrombotic events (including myocardial infarction and stroke) during the use of non-steroidal anti-inflammatory drugs (NSAIDs), in particular the so called selective cyclo-oxygenase-2 (COX 2) inhibitors ...
Brouwers, Jacobus R.B.J., Laar, Mart A.F.J. van de, Vonkeman, Harald E.   +2 more
core   +10 more sources

Aspirin potentiates celecoxib-induced growth inhibition and apoptosis in human non-small cell lung cancer by targeting GRP78 activity

Therapeutic Advances in Medical Oncology, 2020
Background: Aspirin has recently emerged as an anticancer drug, but its therapeutic effect on lung cancer has been rarely reported, and the mechanism of action is still unclear.
Xiangyu Zhang, Jia Chen, Cheng Cheng, Ping Li, Fangfang Cai, Huangru Xu, Yanyan Lu, Nini Cao, Jia Liu, Jigang Wang, Zi-Chun Hua, Hongqin Zhuang   +11 more
doaj   +1 more source

Extracellular free water and glutathione in first-episode psychosis-a multimodal investigation of an inflammatory model for psychosis. [PDF]

, 2021
Evidence has been accumulating for an immune-based component to the etiology of psychotic disorders. Advancements in diffusion magnetic resonance imaging (MRI) have enabled estimation of extracellular free water (FW), a putative biomarker of ...
Carter, Cameron S, Daniel Ragland, J, Howell, Amber, Lesh, Tyler A, Maddock, Richard J, Niendam, Tara A, Tanase, Costin, Wang, Huan   +7 more
core  

Can daily intake of aspirin and/or statins influence the behavior of non-muscle invasive bladder cancer? A retrospective study on a cohort of patients undergoing transurethral bladder resection [PDF]

, 2015
Background: This study aimed to evaluate the behavior of non-muscle-invasive bladder cancer (NMIBC) in patients submitted to transurethral bladder resection (TURB) comparing subjects in chronic therapy with aspirin, statins, or both drugs to untreated ...
Alessandro, Zucchi, Andrea, Fuschi, Carbone, Antonio, DE NUNZIO, Cosimo, Elisabetta, Costantini, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Silvestri, Luigi, Yazan Al, Salhi   +9 more
core   +1 more source

The Impact of Nonsteroidal Anti‐Inflammatory Drugs on Radiographic Spinal Progression in Patients With Axial Spondyloarthritis: 10‐Year Results From an Inception Cohort

Arthritis &Rheumatology, EarlyView.
Objective This study aims to investigate the impact of nonsteroidal anti‐inflammatory drug (NSAID) intake on radiographic spinal progression in axial spondyloarthritis (axSpA), considering different NSAID types (COX‐2 inhibitors [COX2i] and nonselective NSAIDs [ns‐NSAIDs]) and disease subgroups (radiographic [r‐axSpA] and nonradiographic [nr‐axSpA ...
Murat Torgutalp, Valeria Rios Rodriguez, Fabian Proft, Mikhail Protopopov, Judith Rademacher, Hildrun Haibel, Joachim Sieper, Martin Rudwaleit, Denis Poddubnyy   +8 more
wiley   +1 more source

Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells

International Journal of Nanomedicine, 2011
Tae-Ho Kim1*, Young-Il Jeong2*, Shu-Guang Jin2, Jian Pei2, Tae-Young Jung1, Kyung-Sub Moon1, In-Young Kim1, Sam-Suk Kang1, Shin Jung1,21Department of Neurosurgery, 2Brain Tumor Research Laboratory, Chonnam National University Research Institute of ...
Jung S., Kang SS, Kim IY, Jung TY, Pei J, Jin SG, Jeong YI, Kim TH   +7 more
doaj  

Whole-gene CRISPR/cas9 library screen revealed targeting STAT6 increased the sensitivity of liver cancer to celecoxib via inhibiting arachidonic acid shunting

Cell Communication and Signaling
Celecoxib, a selective COX-2 inhibitor, has demonstrated anti-liver cancer effects in various preclinical models and clinical traits. However, prolonged use of celecoxib can lead to drug resistance, necessitating higher doses to maintain efficacy, which ...
Chujiao Hu, Zhirui Zeng, Xin Bao, Dahuan Li, Huading Tai, Haohao Zeng, Cheng Luo, Lei Tang, Tengxiang Chen, Shi Zuo   +9 more
doaj   +1 more source

Effect of periocular injection of celecoxib and propranolol on ocular level of vascular endothelial growth factor in a diabetic mouse model [PDF]

International Journal of Ophthalmology, 2016
AIM: To investigate the effects of periocular injection of propranolol and celecoxib on ocular levels of vascular endothelial growth factor (VEGF) in a diabetic mouse model. METHODS: Forty 4-6wk BALB-C male mice weighing 20-25 g were used.
Saman Nassiri, Gholamreza Houshmand, Mostafa Feghhi, Alireza Kheirollah, Mohammad Bahadoram, Nariman Nassiri   +5 more
doaj   +1 more source

Disease activity and cognition in rheumatoid arthritis : an open label pilot study [PDF]

, 2012
Acknowledgements This work was supported in part by NIHR Newcastle Biomedical Research Centre. Funding for this study was provided by Abbott Laboratories.
Birchall, Daniel, Blamire, Andrew M, He, Jiabao, Isaacs, John D, Newton, Julia L, Pearce, Ruth, Raftery, Graham   +6 more
core   +1 more source