Results 241 to 250 of about 1,647,355 (316)

Cell-free DNA methylome and fragmentome analysis for relapse monitoring of Ewing sarcoma. [PDF]

EMBO Mol Med
Richardson SA, Safrastyan A, Karimpour M, Gulati G, Harker PJB, Redfern A, Pearce SP, Makeev VJ, Brennan B, Lee ATJ, Clipson A, Hill SM, Dive C, Rothwell DG, McCabe MG, Mouliere F.   +15 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Cell-free fetal DNA: the new tool in fetal medicine.

, 2015
Chitty, LS, Everett, TR
core  

Application of a modified MSRE-qPCR method for detecting circulating cell-free DNA methylation in cervical cancer. [PDF]

Front Oncol
Liu Y, He T, Chen S, Wang S, Luo Z, Liu H, Liu Q, Luo D.   +7 more
europepmc   +1 more source

Clinical efficacy of plasma cell-free DNA metagenomic next-generation sequencing in diagnosing bloodstream infections

Qun Dai, Lan-min Lai, Qing Zhu, Lei Yuan
openalex   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Non-disruptive in vitro monitoring of cellular states with cell-free DNA methylation. [PDF]

Genome Biol
Hess A, Kovacsovics A, Bachinger F, Vallier L, Kretzmer H, Meissner A.   +5 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Advances in donor-derived cell-free DNA monitoring for solid organ transplantation. [PDF]

Front Immunol
Sairafi D, Foord E, Pettersson L, Uhlin M.   +3 more
europepmc   +1 more source