Results 11 to 20 of about 1,318,238 (218)

Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers

open access: yesCells, 2019
As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders.
Valentina Karin-Kujundzic   +8 more
doaj   +1 more source

Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content

open access: yesBMC Cancer, 2022
Background Circulating cell-free DNA (cfDNA) in the plasma of cancer patients contains cell-free tumour DNA (ctDNA) derived from tumour cells and it has been widely recognized as a non-invasive source of tumour DNA for diagnosis and prognosis of cancer ...
Devika Ganesamoorthy   +9 more
doaj   +1 more source

Endogenous cell-free DNA in fetal bovine serum introduces artifacts to in vitro cell-free DNA models

open access: yesBioTechniques, 2022
Cell-free DNA (cfDNA) is of growing clinical and research significance. In vitro cfDNA models are a useful tool in cfDNA research; however, artifacts in these models may have implications for the interpretation of new and published data.
Bonnita Werner   +2 more
doaj   +1 more source

The Impact of Pre-transplant Cell-free DNA Levels on Leukemia Relapse and Transplant-related Complications in Allogeneic Hematopoietic Stem Cell Transplant Recipients

open access: yesBalkan Medical Journal, 2020
Background: Cell-free DNA, which may be considered as “liquid” biopsy, may serve as a diagnostic and prognostic marker not only in hematological malignancies but in solid tumors as well.
Zeynep Arzu Yegin   +6 more
doaj   +1 more source

Comparison of methods for the isolation of cell-free DNA from cell culture supernatant

open access: yesTumor Biology, 2020
In vitro characterization of cell-free DNA using two-dimensional cell culture models is emerging as an important step toward an improved understanding of the physical and biological characteristics of cell-free DNA in human biology.
Abel Jacobus Bronkhorst   +2 more
doaj   +1 more source

Study the Role of Cell Free DNA in the Diagnosis of Hepatocellular Carcinoma, an Egyptian Study

open access: yesAsian Pacific Journal of Cancer Biology, 2022
Background and objective: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Since the conventional tissue biopsy and AFP have limited value, a new promising diagnostic method” liquid biopsy” has emerged.
Noha Hassan Radwan   +3 more
doaj   +1 more source

Circulating biomarkers to monitor cancer progression and treatment

open access: yesComputational and Structural Biotechnology Journal, 2016
Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still, the standard diagnostic approach relies on the analysis of a single tumor sample from a local or metastatic site that is obtained at a given time point. Due to
Suthee Rapisuwon   +2 more
doaj   +1 more source

Additional file 1: of Obstetrical provider knowledge and attitudes towards cellâ free DNA screening: results of a cross-sectional national survey

open access: yes, 2018
Obstetrical Care Provider Survey. This file contains the sample survey which we sent to obstetrical care providers exploring their knowledge and attitudes towards cell-free DNA screening. This document includes both English and French versions (DOCX 119 kb)
Chan, Wilson   +3 more
openaire   +1 more source

In silico Design of Linear DNA for Robust Cell-Free Gene Expression

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Cell-free gene expression systems with linear DNA expression templates (LDETs) have been widely applied in artificial cells, biochips, and high-throughput screening.
Xinjie Chen, Yuan Lu
doaj   +1 more source

Cell-free mitochondrial DNA copy number variation in head and neck squamous cell carcinoma: A study of non-invasive biomarker from Northeast India

open access: yesTumor Biology, 2017
Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar   +7 more
doaj   +1 more source

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