Results 231 to 240 of about 1,661,955 (279)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Diagnostic and Therapeutic Options in Myocarditis and Inflammatory Cardiomyopathy. [PDF]

Biomedicines
Schultheiss HP, Escher F, Aleshcheva G, Wiegleb G, Baumeier C.   +4 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Cell and Gene Therapy in Equine Ocular Disease. [PDF]

Vet Ophthalmol
Young KAS, Schnabel LV, Gilger BC.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

C. Norman Coleman's Legacy in Radiation Research and Global Health: A Cancer Research and Care Perspective. [PDF]

Disaster Med Public Health Prep
Aryankalayil MJ, Prasanna PGS, Buchsbaum JC.   +2 more
europepmc   +1 more source

Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management. [PDF]

MedComm (2020)
Zhang M, Hou J, Kuang J, Hao L, Yang Z.
europepmc   +1 more source

Clonal tracing of rare anal metastasis in esophageal squamous cell carcinoma: a case report with whole-exome sequencing and multimodal therapy. [PDF]

Front Immunol
Jiang Y, Pu Y, Huang Z, Pei Q, Li M, Xu M.   +5 more
europepmc   +1 more source

Regulatory T cells in the era of cell and gene therapy: biology, clinical translation, and future prospects. [PDF]

Front Immunol
Sato Y.
europepmc   +1 more source