Results 91 to 100 of about 4,735,099 (379)

Multicentre comparison of a diagnostic assay: Aquaporin-4 antibodies in neuromyelitis optica [PDF]

, 2016
Objective Antibodies to cell surface central nervous system proteins help to diagnose conditions which often respond to immunotherapies. The assessment of antibody assays needs to reflect their clinical utility.
Aktas, O. (Orhan), Altintas, A. (Ayse), Barington, T. (Torben), Berki, T. (Tímea), Berthele, A. (Achim), Bertolotto, A. (Antonio), Comabella, M. (Manuel), Costa, C. (Carme), Deniz, G. (Gunnur), Giometto, B., Granieri, L., Hamann, D. (Dörte), Hartung, H.P., Hintzen, R.Q. (Rogier), Höftberger, R. (Romana), Illes, Z. (Zsolt), Jarius, S. (Sven), Kral, V. (Vlastimil), Leite, M.I. (M. Isabel), Lillevang, S.T. (Søren T.), Marignier, R. (Romain), Montalban, X. (Xavier), Nielsen, H.H. (Helle Hvilsted), Nytrova, P. (Petra), Palace, J. (Jacqueline), Paul, F. (Friedemann), Pelt - Gravesteijn, E.D. (Daniëlle) van, Probst, M. (Monika), Reindl, M. (Markus), Rentzsch, K. (Kristin), Ruiz, A. (Anne), Saiz, A. (Albert Abe), Saschenbrecker, S. (Sandra), Schanda, K. (Kathrin), Siva, A. (Aksel), Sobek, O. (Ondrej), Tintoré, M., Trillenberg, P. (Peter), Tuller, F. (Friederike), Vedeler, C. (Christian), Vincent, A.J.P.E. (Arnoud), Waters, P. (Patrick), Wildemann, B. (Brigitte), Woodhall, M. (Mark), Zuliani, L. (Luigi)   +44 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy. [PDF]

, 2018
The rapid screening and isolation of single leukemia cells from blood has become critical for early leukemia detection and tumor heterogeneity interrogation. However, due to the size overlap between leukemia cells and the more abundant white blood cells (
Digman, Michelle A, Lee, Abraham P, Lee, Do-Hyun, Li, Xuan, Ma, Ning   +4 more
core   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

Protocol for the detection of mechanosensitive response of proteins in cultured cells under compressive stress

STAR Protocols
Summary: Here, we present a protocol to detect mechanosensitive responses of proteins in cells under compressive stress. We describe steps for preparing elastic gels to compress cells grown on an imaging chamber.
Chao Wang, Yuhan Wang, Ting Gang Chew
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Protocol for the colocalization of yeast peroxisomal membrane proteins and their binding partners using stimulated emission depletion microscopy

STAR Protocols
Summary: Peroxisomes are highly dynamic organelles that play crucial roles in cellular metabolism. Here, we present a protocol to investigate peroxisomal membrane proteins and their binding partners in the yeast Hansenula polymorpha using stimulated ...
Frank N. Mol, Eline M.F. de Lange, Ida J. van der Klei, Rifka Vlijm   +3 more
doaj   +1 more source

Development of reverse-transcription PCR techniques to analyse the density and sex ratio of gametocytes in genetically diverse Plasmodium chabaudi infections [PDF]

, 2007
We have developed cross-genotype and genotype-specific quantitative reverse-transcription PCR (qRT-PCR) assays to detect and quantify the number of parasites, transmission stages (gametocytes) and male gametocytes in blood stage Plasmodium chabaudi ...
Abdel-Wahab, Alano, Babiker, Bell, Cheeseman, Damien R. Drew, De Roode, De Roode, De Roode, Dye, Ferguson, Ferguson, Foster, Gardner, Gautret, Hamilton, Khan, Mackinnon, Nee, Paterson, Paul, Paul, Paul, Pinheiro, Ranford-Cartwright, Read, Read, Read, Reece, Reece, Reece, Sarah E. Reece, Schall, Schall, Schneider, Shutler, Sinden, Taylor, Taylor, Wargo, Wargo, West, West, West, West   +44 more
core   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Protocol to study monocyte transmigration across primary human liver endothelial cells under physiological shear flow conditions in vitro

STAR Protocols
Summary: Modeling immune cell recruitment by liver endothelial cells in vitro is important to better understand the pathology of chronic inflammatory liver diseases and cancers.
Alex L. Wilkinson, Megan E. Bannister, Ayla O’Keeffe, Chris J. Weston, Patricia F. Lalor, Shishir Shetty, Daniel A. Patten   +6 more
doaj   +1 more source