Results 191 to 200 of about 4,481,323 (329)

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Protocol for genetic dissection of class switch recombination using genome-editing tools

STAR Protocols
Summary: Antibody class switch recombination is achieved through programmed DNA damage, and the processing of programmed DNA lesions requires the coordinated action of many DNA metabolic factors.
Pengfei Dai, Tingting Liu, Dingpeng Yang, Yifeng Luo, Liu Daisy Liu, Xia Xie, Yafang Shang, Xiaojing Liu, Fei-Long Meng   +8 more
doaj  

Synthesis and Use of the Bifunctional Sulfenic Acid Probe BCN-E-BCN for In Vitro and Cell-Based Assays of Protein Oxidation. [PDF]

Curr Protoc, 2022
Micovic K, Satkunarajah T, Carnet A, Hurst M, Viirre R, Olson MF.   +5 more
europepmc   +1 more source

High-Throughput Cell-Based Screening Using Scintillation Proximity Assay for the Discovery of Inositol Phosphatase Inhibitors [PDF]

, 2004
Wei Zheng, Philip E. Brandish, D. Garrett Kolodin, Edward M. Scolnick, Berta Strulovici   +4 more
openalex   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Evaluating functional ligand-GPCR interactions in cell-based assays. [PDF]

Methods Cell Biol, 2021
Sharma S, Checco JW.
europepmc   +1 more source

Cell-Based Fluorescence Assay for Human Immunodeficiency Virus Type 1 Protease Activity

, 2001
Kristina Lindsten, Tat'ána Uhlı́ková, Jan Konvalinka, Maria G. Masucci, Nico P. Dantuma   +4 more
openalex   +1 more source

Use of a T Cell–Based Assay for Monitoring Efficacy of Antituberculosis Therapy [PDF]

, 2004
Stefania Carrara, Donatella Vincenti, Nicola Petrosillo, Massimo Amicosante, Enrico Girardi, Delia Goletti   +5 more
openalex   +1 more source

Fundamentals of rapid injection molding for microfluidic cell-based assays

bioRxiv, 2017
Ulri N. Lee, Xiaojing Su, D. J. Guckenberger, Ashley M. Dostie, Tianzi Zhang, E. Berthier, A. Theberge   +6 more
semanticscholar   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source