Results 191 to 200 of about 1,959,228 (334)

Evaluating functional ligand-GPCR interactions in cell-based assays. [PDF]

Methods Cell Biol, 2021
Sharma S, Checco JW.
europepmc   +1 more source

Supplementary Figure S2 from Functional Profiling: From Microarrays via Cell-Based Assays to Novel Tumor Relevant Modulators of the Cell Cycle [PDF]

, 2023
Dorit Arlt, Wolfgang Huber, Urban Liebel, Christian Schmidt, Meher Majety, Mamatha Sauermann, Heiko Rosenfelder, Stephanie Bechtel, Alexander Mehrle, Danika L. Bannasch, Ingo Schupp, Markus Seiler, Jeremy C. Simpson, Florian Hahne, Petra Moosmayer, Markus Ruschhaupt, Birgit Guilleaume, Ruth Wellenreuther, Rainer Pepperkok, Holger Sültmann, Annemarie Poustka, Stefan Wiemann   +21 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Synthesis and Use of the Bifunctional Sulfenic Acid Probe BCN-E-BCN for In Vitro and Cell-Based Assays of Protein Oxidation. [PDF]

Curr Protoc, 2022
Micovic K, Satkunarajah T, Carnet A, Hurst M, Viirre R, Olson MF.   +5 more
europepmc   +1 more source

An Automated High-Throughput Cell-Based Multiplexed Flow Cytometry Assay to Identify Novel Compounds to Target Candida albicans Virulence-Related Proteins

, 2014
Stella M. Bernardo, Chris Allen, Anna Waller, Susan Young, Tudor I. Oprea, Larry A. Sklar, Samuel A. Lee   +6 more
openalex   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Detection of Microbial Contamination in Nanomaterials Using LAL, rFC and Cell-Based Assays: Implications for Nanotoxicological Hazard Assessment. [PDF]

Nanomaterials (Basel)
Lei P, Zegeye FD, Alswady-Hoff M, Marcolungo C, Danielsen PH, Madsen AM, Wallin H, Vogel U, Zienolddiny-Narui S, Erdem JS.   +9 more
europepmc   +1 more source

Conformation-stabilizing ELISA and cell-based assays reveal patient subgroups targeting three different epitopes of AGO1 antibodies. [PDF]

Front Immunol, 2022
Moritz CP, Do LD, Tholance Y, Vallayer PB, Rogemond V, Joubert B, Ferraud K, La Marca C, Camdessanché JP, Honnorat J, Antoine JC.   +10 more
europepmc   +1 more source

Capillary-valve-based platform towards cell-on-chip mechanotransduction assays

, 2013
Tanja Cloé Hausherr, Hicham Majd, Damien Joss, Arnaud Müller, Dominique P. Pioletti, Martin A. M. Gijs, Christophe Yamahata   +6 more
openalex   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source