Results 191 to 200 of about 4,735,099 (379)

Tissue Immunofluorescence Confirmation of CNS Autoantibodies Identified by Immunoblot or Cell-Based Assay [PDF]

open access: green, 2020
Rania W. Abelhosn   +7 more
openalex   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Fundamentals of rapid injection molding for microfluidic cell-based assays

open access: yesbioRxiv, 2017
Ulri N. Lee   +6 more
semanticscholar   +1 more source

Comparison of cellular-based viability and apoptosis assays on doxorubicin treated colorectal adenocarcinoma cells

open access: bronze, 2016
Thomas Adrian Tiongson   +3 more
openalex   +1 more source

Coupling high-performance thin-layer chromatography with a battery of cell-based assays reveals bioactive components in wastewater and landfill leachates

open access: gold, 2021
Carolin Riegraf   +6 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Utility of Live Cell-Based Assays for Autoimmune Neurology Diagnostics. [PDF]

open access: yesJ Appl Lab Med, 2022
Woodhall M   +4 more
europepmc   +1 more source

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