Delivery of chemotherapeutic drugs in tumour cell-derived microparticles [PDF]
Nature Communications, 2012 Cellular microparticles are vesicular plasma membrane fragments with a diameter of 100-1,000 nanometres that are shed by cells in response to various physiological and artificial stimuli. Here we demonstrate that tumour cell-derived microparticles can be used as vectors to deliver chemotherapeutic drugs.
Ke Tang +13 more
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Mesenchymal stem cell-derived microparticles: a promising therapeutic strategy. [PDF]
Int J Mol Sci, 2014 Mesenchymal stem cells (MSCs) are multipotent stem cells that give rise to various cell types of the mesodermal germ layer. Because of their unique ability to home in on injured and cancerous tissues, MSCs are of great potential in regenerative medicine.
Tan X, Gong YZ, Wu P, Liao DF, Zheng XL.
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Macrophages Discriminate Glycosylation Patterns of Apoptotic Cell-derived Microparticles [PDF]
Journal of Biological Chemistry, 2011 Inappropriate clearance of apoptotic remnants is considered to be the primary cause of systemic autoimmune diseases, like systemic lupus erythematosus. Here we demonstrate that apoptotic cells release distinct types of subcellular membranous particles (scMP) derived from the endoplasmic reticulum (ER) or the plasma membrane.
Rostyslav Bilyy +14 more
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Endothelial Cell-Derived Microparticle [PDF]
, 2020 National Cancer Institute
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Tumor cell-derived microparticles: a new form of cancer vaccine. [PDF]
Oncoimmunology, 2015 For cancer vaccines, tumor antigen availability is currently not an issue due to technical advances. However, the generation of optimal immune stimulation during vaccination is challenging. We have recently demonstrated that tumor cell-derived microparticles (MP) can function as a new form of potent cancer vaccine by efficiently activating type I ...
Zhang H, Huang B.
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The role of microparticles in oxidative stress and inflammation in patients with vascular intimal hyperplasia [PDF]
Journal of International Medical ResearchObjectives Intimal hyperplasia, which is mainly caused by vascular damage during percutaneous coronary intervention, affects the prognosis of patients who undergo percutaneous coronary intervention.
Xu-Lan Wang +6 more
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Cell-derived microparticle and vascular medicine
Japanese Journal of Thrombosis and Hemostasis, 2011 Shosaku� Nomura
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Catabolic effects of endothelial cell-derived microparticles on disc cells: Implications in intervertebral disc neovascularization and degeneration. [PDF]
J Orthop Res, 2016 Pohl PH +11 more
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Endothelial Cell–Derived Microparticles in Allogeneic Hematopoietic Stem Cell Recipients
Transplantation, 2006 BACKGROUND: Alterations of microparticles derived from different cell types are described in a number of diseases associated with inflammation and hemostatic disorders. METHODS: In this prospective study, we firstly analyzed endothelial cell derived microparticles (EMP) in 19 hematopoietic stem cell recipients. Cultured human umbilical vein endothelial
Verena Pihusch +7 more
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Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression. [PDF]
Oncoimmunology, 2016 Ma R +11 more
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