Tumor cell-derived microparticles: a new form of cancer vaccine. [PDF]
Oncoimmunology, 2015 For cancer vaccines, tumor antigen availability is currently not an issue due to technical advances. However, the generation of optimal immune stimulation during vaccination is challenging.
Zhang H, Huang B.
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Mesenchymal stem cell-derived microparticles: a promising therapeutic strategy. [PDF]
Int J Mol Sci, 2014 Mesenchymal stem cells (MSCs) are multipotent stem cells that give rise to various cell types of the mesodermal germ layer. Because of their unique ability to home in on injured and cancerous tissues, MSCs are of great potential in regenerative medicine.
Tan X, Gong YZ, Wu P, Liao DF, Zheng XL.
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A flow cytometric method for characterization of circulating cell-derived microparticles in plasma. [PDF]
J Extracell Vesicles, 2014 Background and aim Previous studies on circulating microparticles (MPs) indicate that the majority of MPs are of a size below the detection limit of most standard flow cytometers. The objective of the present study was to establish a method to analyze MP
Nielsen MH +3 more
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Measuring circulating cell‐derived microparticles [PDF]
Journal of Thrombosis and Haemostasis, 2004 Éva Bíró, Rienk Nieuwland, A. Sturk
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Delivery of chemotherapeutic drugs in tumour cell-derived microparticles [PDF]
Nature Communications, 2012 Cellular microparticles are vesicular plasma membrane fragments with a diameter of 100-1,000 nanometres that are shed by cells in response to various physiological and artificial stimuli. Here we demonstrate that tumour cell-derived microparticles can be used as vectors to deliver chemotherapeutic drugs.
Ke Tang +13 more
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Cell-derived microparticles in atherosclerosis: biomarkers and targets for pharmacological modulation? [PDF]
J Cell Mol Med, 2012 AbstractIntroductionMicroparticle formation, structure and compositionMicroparticle isolation, preparation and measurementMicroparticles as markers of cardiovascular diseasesMicroparticles as actors in cardiovascular diseasesPharmacological modulation of plasma MP concentrationsConclusionCardiovascular diseases remain an important cause of morbi ...
Baron M +3 more
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Pleomorphic Structures in Human Blood Are Red Blood Cell-Derived Microparticles, Not Bacteria. [PDF]
PLoS One, 2016 Background Red blood cell (RBC) transfusions are a common, life-saving therapy for many patients, but they have also been associated with poor clinical outcomes.
Mitchell AJ +10 more
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Freeze-Derived Anisotropic Porous Microparticles for Engineered Mesenchymal Stem Cell Loading and Wound Healing [PDF]
ResearchHydrogel microparticles that can effectively deliver mesenchymal stem cells (MSCs) are expected to accelerate wound repair progress. Attempts in the area are focusing on improving the functions of the microparticles and MSCs to promote the therapeutic ...
Rongwei Cai +4 more
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Platelet-, leucocyte- and red cell-derived microparticles in stored whole blood, with and without leucofiltration, with and without ionising radiation. [PDF]
Blood Transfus, 2018 BACKGROUND Storage lesion, including microparticle formation, has been partially characterised in whole blood, but not in all combinations of pre-storage leucofiltration and/or irradiation.
Saito S +4 more
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Glycoxidated ferritin induces the release of microparticles positive for Toll-like receptors derived from peripheral blood CD14+ cells [PDF]
Archives of Biological Sciences, 2017 Both increased serum ferritin levels and Toll-like receptor (TLR) activation show independent association with the inflammatory processes. During inflammation, cell activation and apoptosis are accompanied by the release of membrane-derived ...
López-Soto Luis Fernando +9 more
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