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Circulating Cell-Derived Microparticles as Biomarkers in Cardiovascular Disease
Biomarkers in Medicine, 2016Cardiovascular diseases (CVDs) are a common cause of death, and a search for biomarkers for risk stratification is warranted. Elevated levels of cell-derived microparticles (MPs) are found in patients with CVD and in groups with risk factors for CVD.
Åsa, Thulin +3 more
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Cell-Derived Microparticles/Exosomes in Neuroinflammation
2017The roles of cell-derived microparticles (MP) in neuroinflammatory disorders are increasingly recognized as fundamental. Exosomes are now established as a well-defined subclass of MP. A major function is transport of many inflammatory mediators, now including gene-modulating RNA transcripts.
Lawrence L. Horstman +2 more
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Statin and endothelial cell-derived microparticles
Thrombosis and Haemostasis, 2008Thromb Haemost 2008; 100: 377–378 Microparticles (MP) are small membrane vesicles that are released from many different cell types by a process of exocytic budding of the plasma membrane (1). Because MP disseminate various bioactive effectors originating from the parent cells, they can alter vascular function and may induce biological responses ...
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“Kill” the messenger: Targeting of cell-derived microparticles in lupus nephritis
Autoimmunity Reviews, 2016Immune complex (IC) deposition in the glomerular basement membrane (GBM) is a key early pathogenic event in lupus nephritis (LN). The clarification of the mechanisms behind IC deposition will enable targeted therapy in the future. Circulating cell-derived microparticles (MPs) have been proposed as major sources of extracellular autoantigens and ICs and
Nielsen, Christoffer T. +3 more
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Potential roles of cell-derived microparticles in ischemic brain disease
Neurological Research, 2009The objective of this study is to review the role of cell-derived microparticles in ischemic cerebrovascular diseases.An extensive PubMed search of literature pertaining to this study was performed in April 2009 using specific keyword search terms related to cell-derived microparticles and ischemic stroke.
Lawrence L, Horstman +7 more
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Cell-derived microparticles after exercise in individuals with G6PD Viangchan
Clinical Hemorheology and Microcirculation, 2015Abstract Glucose-6-phospate dehydrogenase (G6PD) deficient cells are sensitive to oxidative damage leading to the formation of microparticles (MPs). Therefore, we examined the concentration of MPs and changes in the antioxidant balance after an acute strenuous exercise (SEx) and moderate-intensity exercise (MEx).
Makamas, Chanda +3 more
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Cell-Derived Microparticles Promote Coagulation after Moderate Exercise
Medicine & Science in Sports & Exercise, 2011Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis.This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clearance, and activity of MP before and after exercise ...
Maik, Sossdorf +4 more
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Effect of strenuous physical exercise on circulating cell-derived microparticles
Clinical Hemorheology and Microcirculation, 2011Strenuous exercise is associated with an inflammatory response involving the activation of several types of blood cells. In order to document the specific activation of these cell types, we studied the effect of three maximal exercise tests conducted to exhaustion on the quantitative and qualitative pattern of circulating cell-derived microparticles ...
Chaar, Vicky +7 more
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The variability of cell-derived microparticles and the age of healthy blood donors
Laboratory MedicineAbstract Introduction Cell-derived microparticles that promote coagulation can lead to transfusion-related complications. Although age-dependent changes in hemostasis are known, the impact of donor age on microparticle concentration variability remains largely unexplored. We sought to determine
Surada Lerdwana +3 more
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