Proteome of endothelial cell-derived procoagulant microparticles
Microparticles (MP) are small membrane vesicles that are released from cells upon activation or during apoptosis. Cellular MP in body fluids constitute a heterogeneous population, differing in cellular origin, numbers, size, antigenic composition and functional properties.
E. Tremoli+7 more
openaire +6 more sources
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot+10 more
doaj +1 more source
Polarizabilities of microparticles in relativistic field theory [PDF]
The article determine a relativistic tensor of the second rank containing the vectors of the electric and magnetic polarization of the medium, based on the Maxwell equations and the determination of the charge density and polarization current of a structural microparticle.
arxiv +1 more source
Inhibition of platelet activation prevents the P-selectin and integrin-dependent accumulation of cancer cell microparticles and reduces tumor growth and metastasis in vivo [PDF]
International audienceVenous thromboembolism constitutes one of the main causes of death during the progression of a cancer. We previously demonstrated that tissue factor (TF)-bearing cancer cell-derived microparticles accumulate at the site of injury in
Darbousset, Roxane+4 more
core +3 more sources
Background Circulating microparticles have emerged as biomarkers and effectors of vascular disease. Elevated rates of cardiovascular disease are seen in HIV‐1–seropositive individuals.
Jamie G. Hijmans+9 more
doaj +1 more source
Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation [PDF]
Objective: Increased levels of circulating tissue factor (TF) in the form of microparticles increase the risk of thrombosis. However, any direct influence of microparticle-associated TF on vascular endothelial cell proliferation is not known.
Collier, Mary E. W., Ettelaie, Camille
core +1 more source
Microparticles: potential new contributors to the pathogenesis of systemic sclerosis?
Background Microparticles (MPs) are membrane-derived vesicles released from cells undergoing activation or apoptosis with diverse proinflammatory and prothrombotic activities, that have been implicated in the pathogenesis of systemic sclerosis (SSc).
Sandra Maximiano de Oliveira+4 more
doaj +1 more source
Climacteric Lowers Plasma Levels of Platelet-Derived Microparticles: A Pilot Study in Pre-versus Postmenopausal Women [PDF]
Background: Climacteric increases the risk of thrombotic events by alteration of plasmatic coagulation. Up to now, less is known about changes in platelet-(PMP) and endothelial cell-derived microparticles (EMP). Methods: In this prospective study, plasma
Andreas Rank+43 more
core +3 more sources
Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis
Background We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation.Design and Methods Circulating microparticles ...
Romaric Lacroix+14 more
doaj +1 more source
Simultaneous and independent topological control of identical microparticles in non-periodic energy landscapes [PDF]
Topological protection ensures stability of information and particle transport against perturbations. We explore experimentally and computationally the topologically protected transport of magnetic colloids above spatially inhomogeneous magnetic patterns, revealing that transport complexity can be encoded in both the driving loop and the pattern ...
arxiv +1 more source