Results 71 to 80 of about 8,914,547 (304)
Optimization of serum-free fermentation processes for antibody production
Büntemeyer H, Lütkemeyer D, Lehmann J. Optimization of serum-free fermentation processes for antibody production. Cytotechnology. 1991;5(1):57-67.Serum free fermentation procedures of cell cultures have got a wide application in production of ...
Lehmann, Jürgen +2 more
core +1 more source
Anniversary Party for Kids, Roseland Free Public Library (Roseland, N.J.)
Anniversary Party for Kids, Roseland Free Public Library (Roseland, N.J.)
core +3 more sources
Laboratory automation in the biopharmaceutical industry as a rule requires contracted service from highly professional automation solution provider, at times involving the purchase and development of specialized or customized hardware and software, which
Jie Ding, Kee Wee Tan, Xiaoyue Chen
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Phosphatidylinositol (PI) is essential for numerous cell functions and is generated by consecutive reactions catalyzed by CDP-diacylglycerol synthase (CDS) and PI synthase.
Mark G. Waugh +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Abstract Regulated secretion occurs when the ceil detects a signal, vesicles containing the secretory product fuse with the plasma membrane of the cell, and the contents are released into the extracellular space. This mechanism is called exocytosis. Many laboratories around the world have studied exocytosis for the past couple of decades,
openaire +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Columbus Free Press newsletter
Newsletter sent to Columbus Free Press staff and volunteers, documenting the current financial status of the newspaper and relevant news. The Columbus Free Press began as a bi-weekly publication in Columbus, Ohio, in 1970.
Columbus Free Press (Publisher)
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

