Results 41 to 50 of about 380,699 (255)
Maternal urinary cell free fetal DNA in relation to gestational age
Middle East Fertility Society Journal, 2016 Objectives: To evaluate the presence of cell-free fetal DNA in the maternal urine in relation to gestational age as a potential source for non-invasive prenatal diagnosis. Material and methods: One hundred and sixty normal pregnant women were included in
Mona Mohamed Shaban +6 more
doaj +1 more source
Total number of reads affects the accuracy of fetal fraction estimates in NIPT
Molecular Genetics & Genomic Medicine, 2021 Background Sufficient fetal fraction (FF) is crucial for quality control of NIPT (Non‐Invasive Prenatal Test) results. Different factors influencing bioinformatic estimation of FF should be considered when implementing NIPT.
Ieva Miceikaitė +3 more
doaj +1 more source
Cell-free fetal DNA and non-invasive prenatal diagnosis [PDF]
British Journal of General Practice, 2009 Currently in the UK, prenatal diagnosis of genetic conditions and Down's syndrome requires invasive diagnostic tests such as amniocentesis and chorionic villus sampling (CVS). Procedural related miscarriage rates of about 1% have been quoted for these tests which are not usually done before 11 weeks' gestation.1 Annually in the UK, 32 000 women have an
Imran, Rafi, Lyn, Chitty
openaire +2 more sources
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
Cells, 2019 As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders.
Valentina Karin-Kujundzic +8 more
doaj +1 more source
Veterinary Integrative Sciences, 2023 Cell-free fetal DNA (cffDNA) from fetal calves was isolated in the bovine maternal plasma in the fifth week of pregnancy, accounting for around 10% of the total.
Thi Thanh Khuong Tran +7 more
doaj +1 more source
Cell-free fetal DNA levels in pregnancies conceived by IVF [PDF]
Human Reproduction, 2005 Increased second-trimester levels of maternal serum HCG in IVF conceptions lead to an increased false-positive rate in Down syndrome screening. Increased levels of cell-free fetal DNA (cffDNA) in maternal plasma have been correlated with increased HCG levels.
Phillip D, Pan +5 more
openaire +2 more sources
Cell-free Fetal DNA in Maternal Circulation after Amniocentesis [PDF]
Clinical Chemistry, 2003 After amniocentesis, 5–20% of patients have evidence of fetal-maternal hemorrhage as indicated by increases in maternal serum α-fetoprotein (1)(2)(3)(4)(5) or by the Betke–Kleihauer test (6)(7)(8). The Betke–Kleihauer test can differentiate fetal from maternal erythrocytes by the relative resistance of hemoglobin F-containing cells to acid elution, and
Osamu, Samura +7 more
openaire +2 more sources
Reproductive Medicine and Biology, 2021 Purpose Although non‐invasive prenatal testing (NIPT) based on cell‐free DNA (cfDNA) in maternal plasma has been prevailing worldwide, low levels of fetal DNA fraction may lead to false‐negative results. Since fetal cells in maternal blood provide a pure
Noriko Ito +11 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source