Results 21 to 30 of about 380,699 (255)

Implementation of circulating cell-free DNA screening for fetal aneuploidies

Advances in Laboratory Medicine
Circulating cell-free DNA (cfDNA) consists of extracellular DNA fragments that circulate in the bloodstream and derived from apoptotic cells such as hematopoietic cells or placental trophoblast cells during pregnancy.
Madrigal Bajo Irene, Jodar Bifet Meritxell, Badenas Orquin Celia   +2 more
doaj   +3 more sources

Cell-free fetal DNA and adverse outcome in low risk pregnancies

European Journal of Obstetrics, Gynecology and Reproductive Biology, 2013
To analyze in a large prospective cohort study of low risk pregnancies whether cell-free fetal (cff) DNA in maternal plasma of the second trimester might be associated with the development of preeclampsia, preterm delivery, and small for gestational age.A subset of a large prospective cohort study in serological RhD negative pregnant women with RHD ...
Tobias J Legler
exaly   +4 more sources

Screening for Fetal Aneuploidy and Sex Chromosomal Anomalies in a Pregnant Woman With Mosaicism for Turner Syndrome—Applications and Advantages of Cell-Based NIPT

Frontiers in Genetics, 2021
Background: Cell-free NIPT and cell-based NIPT are risk-free testing options using maternal blood samples to screen for fetal aneuploidies, but the methods differ.
Line Dahl Jeppesen, Line Dahl Jeppesen, Lotte Hatt, Ripudaman Singh, Palle Schelde, Lotte Andreasen, Sara Markholt, Dorte L. Lildballe, Dorte L. Lildballe, Ida Vogel, Ida Vogel   +10 more
doaj   +1 more source

Evaluation of The Relationship between Cell-Free DNA Fetal Fraction of The Circulatory System and Fetal and Maternal Pregnancy Prognosis: A Prospective Study [PDF]

International Journal of Fertility and Sterility, 2023
Background: Non-invasive prenatal testing (NIPT), sometimes called noninvasive prenatal screening (NIPS), is a non-invasive prenatal genetic test using cell-free DNA in maternal blood.
Khadije Rezaie Keikhaie, Maryam Moshfeghi, Leli Rezaie Kahkhaie, Mahya Eftekhari, Sanaz Ajami, Forough Forghani, Mahdi Afshari   +6 more
doaj   +1 more source

Factors Affecting the Fetal Fraction in Noninvasive Prenatal Screening: A Review

Frontiers in Pediatrics, 2022
A paradigm shift in noninvasive prenatal screening has been made with the discovery of cell-free fetal DNA in maternal plasma. Noninvasive prenatal screening is primarily used to screen for fetal aneuploidies, and has been used globally.
Cechuan Deng, Cechuan Deng, Shanling Liu, Shanling Liu   +3 more
doaj   +1 more source

High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing. [PDF]

PLoS ONE, 2012
BACKGROUND: Fetal DNA in maternal urine, if present, would be a valuable source of fetal genetic material for noninvasive prenatal diagnosis. However, the existence of fetal DNA in maternal urine has remained controversial.
Nancy B Y Tsui, Peiyong Jiang, Katherine C K Chow, Xiaoxi Su, Tak Y Leung, Hao Sun, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo   +8 more
doaj   +1 more source

Cell-free DNA for the detection of fetal aneuploidy [PDF]

Fertility and Sterility, 2018
Screening for fetal aneuploidy via cell-free DNA was described more than two decades ago and has been used clinically by obstetric providers in the United States for more than 5 years. Cell-free DNA affords excellent detection of fetal Down syndrome and other common aneuploidies and thus is sought by patients and providers. However, owing to the source
Tamar Goldwaser, Susan Klugman
openaire   +2 more sources

Cell-free DNA test for pathogenic copy number variations: A retrospective study

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: To evaluate the detection rate (DR) by prenatal cell-free DNA test for pathogenic copy number variations (CNVs)＞2 Mb among pregnancies with fetal ultrasound abnormalities.
Hong-Lei Duan, Jie Li, Wan-Jun Wang, David S. Cram, Wei Liu, Pei-Xuan Cao, Xiang-Yu Zhu, Ya-Li Hu   +7 more
doaj   +1 more source

Measurement of fetal fraction in cell-free DNA from maternal plasma using a panel of insertion/deletion polymorphisms. [PDF]

PLoS ONE, 2017
OBJECTIVE:Cell-free DNA from maternal plasma can be used for non-invasive prenatal testing for aneuploidies and single gene disorders, and also has applications as a biomarker for monitoring high-risk pregnancies, such as those at risk of pre-eclampsia ...
Angela N Barrett, Li Xiong, Tuan Z Tan, Henna V Advani, Rui Hua, Cecille Laureano-Asibal, Richie Soong, Arijit Biswas, Niranjan Nagarajan, Mahesh Choolani   +9 more
doaj   +1 more source

Cell Free Fetal DNA: Marker for Predicting Pregnancy Outcomes. [PDF]

Indian J Clin Biochem, 2017
Das SK, Saha MM.
europepmc   +4 more sources