Effect of cell-free fetal DNA on spontaneous preterm labor
Inflammatory phenomenon, including cell-free fetal DNA (cffDNA), is one of the various causes of preterm delivery. Always, there is a trend in the prediction and prevention of preterm labor.
Rogaye Darghahi +5 more
doaj +4 more sources
Cell-free fetal DNA and cell-free total DNA levels in spontaneous abortion with fetal chromosomal aneuploidy. [PDF]
Cell-free fetal DNA and cell-free total DNA in maternal circulation have been proposed as potential markers for noninvasive monitoring of the placental condition during the pregnancy. However, the correlation of and change in cell-free fetal DNA and cell-
Ji Hyae Lim +7 more
doaj +5 more sources
Cell-free fetal DNA coming in all sizes and shapes. [PDF]
AbstractCell‐free fetal DNA analysis has an established role in prenatal assessments. It serves as a source of fetal genetic material that is accessible non‐invasively from maternal blood. Through the years, evidence has accumulated to show that cell‐free fetal DNA molecules are derived from placental tissues, are mainly of short DNA fragments and have
Chiu RWK, Lo YMD.
europepmc +4 more sources
Estimation of cell-free fetal DNA fraction from maternal plasma based on linkage disequilibrium information [PDF]
Cell-free fetal DNA fraction (FF) in maternal plasma is a key parameter affecting the performance of noninvasive prenatal testing (NIPT). Accurate quantitation of FF plays a pivotal role in these tests. However, there are few methods that could determine
Jia Ju +8 more
doaj +2 more sources
Fetal Nucleated Red Blood Cells Preferable Than Cell-Free Fetal DNA for Early Determination of Gender Among Invasive and Non-Invasive Source Using Novel Four Genes Multiplex PCR [PDF]
Norah F Alhur,1 Nourah H Al Qahtani,2 Entissar S AlSuhaibani,1 Eman Alsulmi,2 Noor B Almandil,3 Sayed AbdulAzeez,4 J Francis Borgio4 1College of Science, Zoology Department, King Saud University, Riyadh, Saudi Arabia; 2Obstetrics and Gynecology ...
Alhur NF +6 more
doaj +2 more sources
Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models [PDF]
In animal models, maternal obesity is associated with development of neurodevelopmental disorder like phenotypes. Here the authors show in a macaque model that in obese dams, cell-free fetal DNA methylation, inflammatory cytokines, and metabolites ...
Benjamin I. Laufer +15 more
doaj +2 more sources
Cell-free DNA fetal fraction and preterm birth [PDF]
Cell-free deoxyribonucleic acid (DNA) is increasingly being used to screen for fetal aneuploidy. The majority of fetal cell-free DNA in the maternal blood results from release from the syncytiotrophoblast as a result of cellular apoptosis and necrosis.
Lorraine Dugoff +2 more
exaly +3 more sources
Cell-free fetal DNA and spontaneous preterm birth. [PDF]
Abstract Inflammation is known to play a key role in preterm and term parturition. Cell-free fetal DNA (cff-DNA) is present in the maternal circulation and increases with gestational age and some pregnancy complications (e.g. preterm birth, preeclampsia).
van Boeckel SR +3 more
europepmc +5 more sources
Cell-free fetal DNA testing and its correlation with prenatal indications [PDF]
Highlights The whole-genome sequencing of cell-free fetal DNA from maternal plasma is an effective prenatal screening tool for pregnancies with various prenatal indications.
Jing-wei Wang +9 more
doaj +2 more sources
Endogenous cell-free DNA in fetal bovine serum introduces artifacts to in vitro cell-free DNA models
Cell-free DNA (cfDNA) is of growing clinical and research significance. In vitro cfDNA models are a useful tool in cfDNA research; however, artifacts in these models may have implications for the interpretation of new and published data.
Bonnita Werner +2 more
doaj +3 more sources

