Results 101 to 110 of about 239,910 (281)

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source

A multifaceted strategy for intra- and extracellular nucleic acid regulation to alleviate intervertebral disc degeneration

Nature Communications
Abnormal accumulation of both intracellular and extracellular free nucleic acids drives chronic inflammation in intervertebral disc degeneration (IVDD).
Lan Zhao, Kaiyu Liang, Wenqiang Cheng, Xizhuo Zhou, Libin Yang, Xinning Mao, Weihui Qi, Hongting Jin, Wei Zhang, Hao Pan, Dong Wang   +10 more
doaj   +1 more source

An Overview of Circulating Cell-Free Nucleic Acids in Diagnosis and Prognosis of Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci, 2023
Tierno D, Grassi G, Zanconati F, Bortul M, Scaggiante B.   +4 more
europepmc   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Global Trends in Research on Cell-Free Nucleic Acids in Obstetrics and Gynecology during 2017-2021. [PDF]

J Clin Med, 2022
Gao W, Yang H, Cheng W, Wang X, Li D, Shi B.   +5 more
europepmc   +1 more source

Supplementary Methods, Supplementary Table 1, Supplementary Figure Legends from Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers

, 2023
Lino Möhrmann, Helen J. Huang, David S. Hong, Apostolia M. Tsimberidou, Siqing Fu, Sarina A. Piha‐Paul, Vivek Subbiah, Daniel D. Karp, Aung Naing, Anne Krug, Daniel Enderle, Tina Priewasser, Mikkel Noerholm, Erez Eitan, Christine M. Coticchia, Georg Stoll, Lisa-Marie Jordan, Cathy Eng, Scott Kopetz, Johan Skog, Funda Meric‐Bernstam, Filip Jankú   +21 more
openalex   +1 more source

A Novel, Highly Sensitive Nucleic Acid Amplification Test Assay for the Diagnosis of Loiasis and its Use for Detection of Circulating Cell-Free DNA [PDF]

, 2023
Sasisekhar Bennuru, Frimpong Kodua, Papa Makhtar Drame, Eric Dahlstrom, Thomas B. Nutman   +4 more
openalex   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Bioanalytical Applications of Graphene Quantum Dots for Circulating Cell-Free Nucleic Acids: A Review. [PDF]

ACS Omega, 2022
Ratre P, Jain B, Kumari R, Thareja S, Tiwari R, Srivastava RK, Goryacheva IY, Mishra PK.   +7 more
europepmc   +1 more source

Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels

Advanced Functional Materials, EarlyView.
This study establishes a materials‐based design framework for polymer hydrogels in tissue clearing, linking physicochemical properties to performance in tissue processing, labeling, and imaging. By analyzing rheology, swelling, porosity, antibody diffusion, mechanical performance, and thermochemical stability across platforms, this work provides a ...
Sangjae Kim, Siheon Lee, Jinsoo Na, James Sangmin Choo, Inho Kim, Junsang Doh, Jeong‐Yun Sun, Chang Yeol Lee, Juhyuk Park   +8 more
wiley   +1 more source