Results 141 to 150 of about 6,347,699 (399)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Functionalizing cell-free systems with CRISPR-associated proteins: Application to RNA-based circuit engineering [PDF]
, 2021 François-Xavier Lehr +5 more
openalex +1 more source
The Diversification of Cell Death and Immunity: Memento Mori.
, 2019 Why do cells have so many ways to die? Why does "cellular suicide" exist at all? In the war against pathogens and rogue cells, organisms developed cellular suicide as a last resort. Fighting an evolutionary arms race, cell death pathways have adapted and
Legrand, AJ +3 more
core +1 more source
Viruses do replicate in cell-free systems [PDF]
Proceedings of the National Academy of Sciences, 2012 Klingeborn et al. (1) reported a systematic study of the infectivity of transmissible spongiform encephalopathy (TSE) infectious agent generated de novo in cell-free reactions. They convincingly demonstrated the generation of new TSE infectivity in reactions primed by infected brain homogenates.
openaire +2 more sources
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Label-free single-cell protein quantification using a drop-based mix-and-read system [PDF]
, 2015 Alireza Abbaspourrad +13 more
openalex +1 more source
Emerging Methods for Efficient and Extensive Incorporation of Non Canonical Amino Acids using Cell-free Systems [PDF]
, 2020 Yang‐Chang Wu +5 more
openalex +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Knowing one's place: a free-energy approach to pattern regulation.
, 2015 Understanding how organisms establish their form during embryogenesis and regeneration represents a major knowledge gap in biological pattern formation.
Levin, M +3 more
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The impact of the introduction of the new FET system at colleges in the Free State with special reference to Motheo FET College [PDF]
, 2006 Thesis (M. Tech.) - Central University of Technology, Free State, 2006This study provides an analysis of the impact of the introduction of the FET system at Colleges in the Free State, with reference to Motheo FET College.
Mosholi, Thandeka Judith
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