Results 161 to 170 of about 6,347,699 (399)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Identification of candidate mitochondrial inheritance determinants using the mammalian cell-free system. [PDF]

Elife, 2023
Zuidema D, Jones A, Song WH, Zigo M, Sutovsky P.   +4 more
europepmc   +1 more source

The biosynthesis of plasmalogens in a cell‐free system

FEBS Letters, 1970
Wykle, Robert L., Blank, M.L., Snyder, Fred   +2 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

alpha 2-chimaerin, a Cdc42/Rac1 regulator, is selectively expressed in the rat embryonic nervous system and is involved in neuritogenesis in N1E-115 neuroblastoma cells

, 2001
Neuronal differentiation involves Rac and Cdc42 GTPases. alpha -Chimaerin, a Rac/Cdc42 regulator, occurs as alpha 1- and alternatively spliced Src homology 2 (SH2) domain-containing alpha 2-isoforms. alpha 2-chimaerin mRNA was highly expressed in the rat
Christine Hall, Giovanna Ferrari, Nansi Cann, Teo, M., Clinton Monfries, Michael, G.J., Cann, N., Louis Lim, Ferrari, G., Jacobs, T., Mabel Teo, Hall, C., Tom Jacobs, Lim, L., Gregory J. Michael, Monfries, C.   +15 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Facade-Based Bicelles as a New Tool for Production of Active Membrane Proteins in a Cell-Free System. [PDF]

Int J Mol Sci, 2023
Goncharuk MV, Vasileva EV, Ananiev EA, Gorokhovatsky AY, Bocharov EV, Mineev KS, Goncharuk SA.   +6 more
europepmc   +1 more source

Notice of Concern: Ellerby et al., Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases [PDF]

, 2013

openalex   +1 more source

Corrigendum: Effective use of linear DNA in cell-free expression systems [PDF]

, 2022
Megan A. McSweeney, Mark P. Styczynski
openalex   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source