Analysis of the Innovation Trend in Cell-Free Synthetic Biology [PDF]
Life, 2021 Cell-free synthetic biology is a maturing field that aims to assemble biomolecular reactions outside cells for compelling applications in drug discovery, metabolic engineering, biomanufacturing, diagnostics, and education.
Conary Meyer +5 more
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Biological Materials: The Next Frontier for Cell-Free Synthetic Biology [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Advancements in cell-free synthetic biology are enabling innovations in sustainable biomanufacturing, that may ultimately shift the global manufacturing paradigm toward localized and ecologically harmonized production processes.
Richard J. R. Kelwick +4 more
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Cell-Free Synthetic Biology Platform for Engineering Synthetic Biological Circuits and Systems [PDF]
Methods and Protocols, 2019 Synthetic biology brings engineering disciplines to create novel biological systems for biomedical and technological applications. The substantial growth of the synthetic biology field in the past decade is poised to transform biotechnology and medicine.
Dohyun Jeong +6 more
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The future of cell-free synthetic biology [PDF]
Biotechnology NotesCell-free synthetic biology aims at the targeted replication, design, and modification of life processes in open systems by breaking free of constraints such as cell membrane barriers and living cell growth. The beginnings of this systematized technology,
Yuan Lu
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Cell-free synthetic biology: Engineering in an open world [PDF]
Synthetic and Systems Biotechnology, 2017 Cell-free synthetic biology emerges as a powerful and flexible enabling technology that can engineer biological parts and systems for life science applications without using living cells.
Yuan Lu
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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis [PDF]
Methods and Protocols, 2019 Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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Cell-free synthetic biology: Orchestrating the machinery for biomolecular engineering [PDF]
Biotechnology Notes, 2022 Due to inherent complexity, incompatibility, and variability in living cell systems, biomolecular engineering faces significant obstacles. To find novel solutions to these issues, researchers have turned to cell-free synthetic biology (CFSB), a ...
Xiaomei Lin, Ting Wang, Yuan Lu
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Bottom-Up Construction of Complex Biomolecular Systems With Cell-Free Synthetic Biology [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 Cell-free systems offer a promising approach to engineer biology since their open nature allows for well-controlled and characterized reaction conditions. In this review, we discuss the history and recent developments in engineering recombinant and crude
Nadanai Laohakunakorn +6 more
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Cell-free synthetic biology for in vitro biosynthesis of pharmaceutical natural products [PDF]
Synthetic and Systems Biotechnology, 2018 Natural products with significant biological activities continuously act as rich sources for drug discovery and development. To harness the potential of these valuable compounds, robust methods need to be developed for their rapid and sustainable ...
Jian Li, Lingkai Zhang, Wanqiu Liu
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Opportunities to accelerate extracellular vesicle research with cell‐free synthetic biology [PDF]
Journal of Extracellular Biology, 2023 Extracellular vesicles (EVs) are lipid‐membrane nanoparticles that are shed or secreted by many different cell types. The EV research community has rapidly expanded in recent years and is leading efforts to deepen our understanding of EV biological ...
Richard J. R. Kelwick +4 more
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