Results 161 to 170 of about 371,071 (337)

Supplementary figure legend unmarked from A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers

, 2023
Georg Karpel‐Massler, Basil A. Horst, Chang Shu, Lily Chau, Takashi Tsujiuchi, Jeffrey N. Bruce, Peter Canoll, Lloyd A. Greene, James M. Angelastro, Markus D. Siegelin   +9 more
openalex   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

Enhanced Intracellular Translocation of Gold Nanoparticles Functionalized with TAT Peptide into Cancer Cell Lines

مجله دانشکده پزشکی اصفهان, 2015
Background: Reduced toxicity and ease of modification make gold nanoparticles (GNPs) suitable for targeted delivery and bioimaging via conjugating cell-penetrating peptides (CPPs). This study aimed to assess the enhanced penetration of gold nanoparticles
Sedigheh Khamehchian, Saman Hosseinkhani, Rasool Madani, Maryam Nikkhah   +3 more
doaj  

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Peptide phosphorylation in the design of a vector for intracellular drug delivery based on the cell-penetrating peptide penetratin [PDF]

, 2013
Reto Sauder
openalex   +1 more source

Correction: A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia [PDF]

, 2022
Yiran Chen, Xiaoling Xie, Anqin Wu, Lei Wang, Yuxing Hu, Honghao Zhang, Yuhua Li   +6 more
openalex   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

The light chain of tetanus toxin bound to arginine-rich cell-penetrating peptide inhibits cortical reaction in mouse oocytes [PDF]

, 2023
Omar Guillermo Klinsky, Paula Wetten, Emilia Zanni-Ruiz, Martín A. Pavarotti, María Victoria Berberián, Marcela A. Michaut   +5 more
openalex   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

47 Gambogic acid delivery using lipid nanoparticles modified with cell-penetrating peptide

, 2016
Mingzhi Zhao, Jingying Li, LuoMin Xiao, Jie Zeng, DanChun Zhang, Robert J. Lee, Lesheng Teng   +6 more
openalex   +1 more source