Results 291 to 300 of about 1,820,621 (315)
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa +7 more
wiley +1 more source
Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen
Fluorescent polymeric nanofibers and nanorods are produced as ratiometric sensors of two important physiological parameters: pH and oxygen. They operate by dual Forster resonance energy transfer from large number of energy donor dyes to limited number of two distinct energy acceptors, enabling simultaneous sensing of pH and oxygen.
Rémi Pelletier +2 more
wiley +1 more source
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji +8 more
wiley +1 more source
Compression‐Tension‐Asymmetry and Stiffness Nonlinearity of Collagen‐Matrigel Composite Hydrogels
Self‐assembled collagen hydrogel matrices are widely used in tissue engineering applications. These matrices stiffen and contract laterally under tension due to fiber alignment and soften and collapse under compression due to fiber buckling. It is demonstrated that filler materials, such as Matrigel, linearize the mechanical behavior of collagen ...
David Böhringer +9 more
wiley +1 more source
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
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Cell–cell communication: new insights and clinical implications
Signal Transduction and Targeted TherapyMulticellular organisms are composed of diverse cell types that must coordinate their behaviors through communication. Cell–cell communication (CCC) is essential for growth, development, differentiation, tissue and organ formation, maintenance, and ...
Jimeng Su +6 more
semanticscholar +1 more source
Quorum sensing: cell-to-cell communication in bacteria.
Annual Review of Cell and Developmental Biology, 2005C. Waters, B. Bassler
semanticscholar +1 more source
Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing.
Annual Review of Genetics, 2001C. Fuqua, M. Parsek, E. Greenberg
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