Results 101 to 110 of about 10,043,453 (323)

Cell mechanics, environmental geometry, and cell polarity control cell-cell collision outcomes [PDF]

open access: yesarXiv
Interactions between crawling cells, which are essential for many biological processes, can be quantified by measuring cell-cell collisions. Conventionally, experiments of cell-cell collisions are conducted on two-dimensional flat substrates, where colliding cells repolarize and move away upon contact with one another in "contact inhibition of ...
arxiv  

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Position Statement: Minimal Criteria for Reporting Veterinary and Animal Medicine Research for Mesenchymal Stromal/Stem Cells in Orthopedic Applications

open access: yesFrontiers in Veterinary Science, 2022
Debbie J. Guest   +7 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Metal and Polymeric Strain Gauges for Si-Based, Monolithically Fabricated Organs-on-Chips

open access: yesMicromachines, 2019
Organ-on-chip (OOC) is becoming the alternative tool to conventional in vitro screening. Heart-on-chip devices including microstructures for mechanical and electrical stimulation have been demonstrated to be advantageous to study structural organization ...
William F. Quirós-Solano   +5 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Deciphering Membrane Proteins Through Deep Learning Models by Revealing Their Locale Within the Cell

open access: yesBioengineering
Membrane proteins constitute essential biomolecules attached to or integrated into cellular and organelle membranes, playing diverse roles in cellular processes. Their precise localization is crucial for understanding their functions.
Mehwish Faiz   +4 more
doaj   +1 more source

Adhesion and volume constraints via nonlocal interactions lead to cell sorting [PDF]

open access: yesarXiv, 2017
We demonstrate how concepts of statistical mechanics of interacting particles can have important implications in the choice of interaction potentials to model qualitative properties of cell aggregates in theoretical biology. We illustrate this by showing cell sorting phenomena for cell groups with different adhesiveness parameters: ranging from well ...
arxiv  

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