Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
3 300 V IGBT / FRD Chipset Design and Development for Traction Application
According to the IGBT characteristics and requirements for traction application, the simulation technique was used on the termination structure design to improve the blocking voltage.
LIU Guo-you +3 more
doaj
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Observations of cellular responses to diamagnetic forces acting on cell components
The magnetooptical measurements of the properties of living cells have a potentially large impact on cellular engineering and biotechnology because the noninvasive approach to applying magnetic fields on cells enables the detection of the dynamics of ...
Masakazu Iwasaka et al
doaj
Ciclosporin reduces paracellin-1 expression and magnesium transport in thick ascending limb cells [PDF]
Cheng‐Chieh Chang +4 more
openalex +1 more source
Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology. [PDF]
High costs and technical limitations of cell sorting and single-cell techniques currently restrict the collection of large-scale, cell-type-specific DNA methylation data.
Barcellos, Lisa F +8 more
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Optical manipulation of microparticles and cells on silicon nitride waveguides
S. Gaugiran +6 more
openalex +1 more source
Crohnʼs disease, hepatosplenic T-cell lymphoma and no biological therapy: Are we barking up the wrong tree? [PDF]
Gordon W. Moran +2 more
openalex +1 more source

