Results 21 to 30 of about 29,730,138 (413)
Specifying sickle cell disease interventions: A study protocol of the Sickle Cell Disease Implementation Consortium (SCDIC) [PDF]
, 2018 Background Sickle cell disease (SCD) is an inherited blood disorder that results in a lifetime of anemia, severe pain, and end-organ damage that can lead to premature mortality.
Baumann, Ana A +4 more
core +2 more sources
Estimating Bacterial and Cellular Load in FCFM Imaging
Journal of Imaging, 2018 We address the task of estimating bacterial and cellular load in the human distal lung with fibered confocal fluorescence microscopy (FCFM). In pulmonary FCFM some cells can display autofluorescence, and they appear as disc like objects in the FCFM ...
Sohan Seth +3 more
doaj +1 more source
Fast, sensitive, and accurate integration of single cell data with Harmony
Nature Methods, 2019 The emerging diversity of single-cell RNA-seq datasets allows for the full transcriptional characterization of cell types across a wide variety of biological and clinical conditions.
I. Korsunsky +8 more
semanticscholar +1 more source
FEBS Letters, 2007 Cell–cell fusion is a highly regulated and dramatic cellular event that is required for development and homeostasis. Fusion may also play a role in the development of cancer and in tissue repair by stem cells. While virus–cell fusion and the fusion of intracellular membranes have been the subject of intense investigation during the past decade, cell ...
Elizabeth H. Chen +3 more
openaire +3 more sources
Multiplexing cell-cell communication [PDF]
Molecular Systems Biology, 2019 AbstractThe engineering of advanced multicellular behaviors, such as the programmed growth of biofilms or tissues, requires cells to communicate multiple aspects of physiological information. Unfortunately, few cell-cell communication systems have been developed for synthetic biology. Here, we engineer a genetically-encoded channel selector device that
John T Sexton, Jeffrey J Tabor
openaire +5 more sources
Endogenous electric fields as guiding cue for cell migration
Frontiers in Physiology, 2015 This review is about the long-range action of endogenous electric fields (EF) within animal organisms. It covers two major topics: 1) the different functions of the EF during development of the organism as well as physiological and pathological roles of ...
Richard H. W. Funk
doaj +1 more source
Cobalt chloride pretreatment promotes cardiac differentiation of human embryonic stem cells under atmospheric oxygen level [PDF]
, 2011 Our previous study demonstrated the direct involvement of the HIF-1α subunit in the promotion of cardiac differentiation of murine embryonic stem cells (ESCs).
Au, KW +8 more
core +1 more source
Lipid Specific Membrane Interaction of Aptamers and Cytotoxicity
Membranes, 2021 We aim to discover diagnostic tools to detect phosphatidylserine (PS) externalization on apoptotic cell surface using PS binding aptamers, AAAGAC and TAAAGA, and hence to understand chemotherapy drug efficacy when inducing apoptosis into cancer cells ...
Md. Ashrafuzzaman +4 more
doaj +1 more source
SCENIC: Single-cell regulatory network inference and clustering
Nature Methods, 2017 We present SCENIC, a computational method for simultaneous gene regulatory network reconstruction and cell-state identification from single-cell RNA-seq data (http://scenic.aertslab.org).
S. Aibar +13 more
semanticscholar +1 more source
Developmental definition of MSCs: New insights into pending questions [PDF]
, 2011 Mesenchymal stem cells (MSCs) are a rare heterogeneous population of multipotent cells that can be isolated from many different adult and fetal tissues.
Cheung, KMC +8 more
core +1 more source