Results 81 to 90 of about 26,893,016 (421)
Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer [PDF]
, 2015 Induced pluripotent stem cells (iPSCs) share similar characteristics of indefinite in vitro growth with embryonic stem cells (ESCs) and may therefore serve as a useful tool for the targeted genetic modification of farm animals via nuclear transfer (NT ...
Alberio, Ramiro +5 more
core +2 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
Nature, 2012 The systematic translation of cancer genomic data into knowledge of tumour biology and therapeutic possibilities remains challenging. Such efforts should be greatly aided by robust preclinical model systems that reflect the genomic diversity of human ...
J. Barretina +60 more
semanticscholar +1 more source
Cell-by-Cell Deconstruction of Stem Cell Niches [PDF]
Cell Stem Cell, 2020 Single-cell sequencing approaches offer exploration of tissue architecture at unprecedented resolution. These tools are especially powerful when deconvoluting highly specialized microenvironments, such as stem cell (SC) niches. Here, we review single-cell studies that map the cellular and transcriptional makeup of stem and progenitor niches and discuss
Anastasia N. Tikhonova +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
The Phagocytic Code Regulating Phagocytosis of Mammalian Cells
Frontiers in Immunology, 2021 Mammalian phagocytes can phagocytose (i.e. eat) other mammalian cells in the body if they display certain signals, and this phagocytosis plays fundamental roles in development, cell turnover, tissue homeostasis and disease prevention.
Tom O. J. Cockram +3 more
doaj +1 more source
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Science, 2016 Single-cell expression profiles of melanoma Tumors harbor multiple cell types that are thought to play a role in the development of resistance to drug treatments. Tirosh et al.
I. Tirosh +36 more
semanticscholar +1 more source
Charismatic Heads of State: The Social Context [PDF]
, 1971 http://deepblue.lib.umich.edu/bitstream/2027.42/50843/1/61 ...
Cell, Charles P.
core
International Journal of Cell Biology, 2010 This special issue on Cell Stress and Cell Death is aimed at bringing together recent developments in the fields of cellular stress and cell death and, in particular, the interplay between cell stress responses and cell death. The special issue opens with a review by S. Fulda et al.
Afshin Samali +4 more
openaire +6 more sources
Cell Docking, Movement and Cell-Cell Interactions of Heterogeneous Cell Suspensions in a Cell Manipulation Microdevice [PDF]
Sensors, 2011 This study demonstrates a novel cell manipulation microdevice for cell docking, culturing, cell-cell contact and interaction by microfluidic manipulation of heterogeneous cell suspensions. Heterogeneous cell suspensions include disparate blood cells of natural killer cells and leukemia cancer cells for immune cell transplantation therapy.
Yu-Wei Chung +4 more
openaire +4 more sources