Results 11 to 20 of about 11,890,652 (305)

Cell adhesion in cancer: Beyond the migration of single cells

open access: yesJournal of Biological Chemistry, 2020
Homeostasis in healthy tissues strongly relies on cell-to-cell adhesion and cell-to-extracellular matrix interactions. For instance, normal epithelial cells maintain tissue structure by adhering to each other and to the extracellular matrix. The proteins
M. Janiszewska, M. C. Primi, T. Izard
semanticscholar   +1 more source

Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients

open access: yesJournal of Infectious Diseases, 2020
In a retrospective study of 39 COVID-19 patients and 32 control participants in China, we collected clinical data and examined the expression of endothelial cell adhesion molecules by enzyme-linked immunosorbent assays.
Ming Tong   +8 more
semanticscholar   +1 more source

Targeted remodeling of breast cancer and immune cell homing niches by exosomal integrins

open access: yesDiagnostic Pathology, 2020
Exosomes represent an important subset of extracellular vesicles involved in inter-cellular communications in health and diseases. Exosomes secreted from cancer and immune cells travel to the specific tissues containing homing niches.
Phyoe Kyawe Myint   +4 more
doaj   +1 more source

The Spike Glycoprotein of SARS-CoV-2 Binds to β1 Integrins Expressed on the Surface of Lung Epithelial Cells

open access: yesViruses, 2021
The spike glycoprotein attached to the envelope of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to and exploits angiotensin-converting enzyme 2 (ACE2) as an entry receptor to infect pulmonary epithelial cells.
Eun Jeong Park   +9 more
doaj   +1 more source

On the adhesion of vesicles by cell adhesion molecules [PDF]

open access: yesBiophysical Journal, 1985
This paper gives a detailed analysis of experiments on the kinetics of aggregation of lipid vesicles containing neural cell adhesion molecules (N-CAM). An explanation for the dependence of the "initial aggregation rate," kagg, on the square of the vesicle concentration is given, accounting both for Brownian motion of the vesicles and shear effects.
D.C. Torney, G.I. Bell
openaire   +2 more sources

Vinculin and Cell-Cell Adhesion [PDF]

open access: yesCell Adhesion and Communication, 1998
Vinculin, a 117-kDa protein, is a constituent of adhesion plaques and adherence junctions in non-muscle cells. We investigated the role of vinculin on the physical strength of cell-cell adhesion by conducting disaggregation assays on aggregates of parental wild-type F9 mouse embryonal carcinoma cells (clone BIM), two vinculin-depleted F9 cell lines ...
Aydin Tozeren   +5 more
openaire   +3 more sources

Modelling adhesion-independent cell migration [PDF]

open access: yes, 2020
A two-dimensional mathematical model for cells migrating without adhesion capabilities is presented and analyzed. Cells are represented by their cortex, which is modelled as an elastic curve, subject to an internal pressure force.
Jankowiak, Gaspard   +4 more
core   +5 more sources

The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin

open access: yesBiomedicines, 2021
Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular matrix proteins, such as fibronectin and collagen; however, whether thrombomodulin regulates the ...
Eiji Kawamoto   +16 more
doaj   +1 more source

Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1

open access: yesCell Communication and Signaling, 2019
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao   +12 more
doaj   +1 more source

Selective Desensitization of Growth Factor Signaling by Cell Adhesion to Fibronectin [PDF]

open access: yes, 2007
Cell adhesion to the extracellular matrix is required to execute growth factor (GF)-mediated cell behaviors, such as proliferation. A major underlying mechanism is that cell adhesion enhances GF-mediated intracellular signals, such as extracellular ...
Asthagiri, Anand R.   +3 more
core   +1 more source

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