Results 11 to 20 of about 11,304,397 (389)

Endothelial cell-cell adhesion and signaling

Experimental Cell Research, 2017
Endothelial cells line blood vessels and provide a dynamic interface between the blood and tissues. They remodel to allow leukocytes, fluid and small molecules to enter tissues during inflammation and infections. Here we compare the signaling networks that contribute to endothelial permeability and leukocyte transendothelial migration, focusing ...
Cerutti, Camilla, Ridley, Anne J
openaire   +9 more sources

Cell adhesion in cancer: Beyond the migration of single cells

Journal of Biological Chemistry, 2020
Homeostasis in healthy tissues strongly relies on cell-to-cell adhesion and cell-to-extracellular matrix interactions. For instance, normal epithelial cells maintain tissue structure by adhering to each other and to the extracellular matrix. The proteins
M. Janiszewska, M. C. Primi, T. Izard
semanticscholar   +1 more source

Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients

Journal of Infectious Diseases, 2020
In a retrospective study of 39 COVID-19 patients and 32 control participants in China, we collected clinical data and examined the expression of endothelial cell adhesion molecules by enzyme-linked immunosorbent assays.
Ming Tong, Yu Jiang, Da Xia, Ying Xiong, Qing Zheng, Fang Chen, L. Zou, Wen Xiao, Yimin Zhu   +8 more
semanticscholar   +1 more source

On the adhesion of vesicles by cell adhesion molecules [PDF]

Biophysical Journal, 1985
This paper gives a detailed analysis of experiments on the kinetics of aggregation of lipid vesicles containing neural cell adhesion molecules (N-CAM). An explanation for the dependence of the "initial aggregation rate," kagg, on the square of the vesicle concentration is given, accounting both for Brownian motion of the vesicles and shear effects.
D.C. Torney, G.I. Bell
openaire   +2 more sources

Vinculin and Cell-Cell Adhesion [PDF]

Cell Adhesion and Communication, 1998
Vinculin, a 117-kDa protein, is a constituent of adhesion plaques and adherence junctions in non-muscle cells. We investigated the role of vinculin on the physical strength of cell-cell adhesion by conducting disaggregation assays on aggregates of parental wild-type F9 mouse embryonal carcinoma cells (clone BIM), two vinculin-depleted F9 cell lines ...
Aydin Tozeren, Weiming Xu, Eileen D. Adamson, Stephen W. Byers, Stephen Wu, Becky Hoxter   +5 more
openaire   +3 more sources

Cell Adhesion at the Tight Junctions: New Aspects and New Functions

Cells, 2023
Tight junctions (TJ) are cell–cell adhesive structures that define the permeability of barrier-forming epithelia and endothelia. In contrast to this seemingly static function, TJs display a surprisingly high molecular complexity and unexpected dynamic ...
Nicolina Wibbe, Klaus Ebnet
doaj   +1 more source

Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1

Cell Communication and Signaling, 2019
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao, Yun Bao, Shushu Ge, Peisen Sun, Jiaojiao Sun, Jianmin Liu, Feng Chen, Li Han, Zhongyuan Cao, Jun Qin, Gilbert C. White, Zhen Xu, Yan-Qing Ma   +12 more
doaj   +1 more source

The Lectin-Like Domain of Thrombomodulin Inhibits β1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin

Biomedicines, 2021
Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular matrix proteins, such as fibronectin and collagen; however, whether thrombomodulin regulates the ...
Eiji Kawamoto, Nodoka Nago, Takayuki Okamoto, Arong Gaowa, Asami Masui-Ito, Yuichi Akama, Samuel Darkwah, Michael Gyasi Appiah, Phyoe Kyawe Myint, Gideon Obeng, Atsushi Ito, Siqingaowa Caidengbate, Ryo Esumi, Takanori Yamaguchi, Eun Jeong Park, Hiroshi Imai, Motomu Shimaoka   +16 more
doaj   +1 more source

Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin

Frontiers in Cell and Developmental Biology, 2020
Integrins are transmembrane proteins that mediate cellular adhesion and migration to neighboring cells or the extracellular matrix, which is essential for cells to undertake diverse physiological and pathological pathways.
Eun Jeong Park, Phyoe Kyawe Myint, Atsushi Ito, Atsushi Ito, Michael G. Appiah, Samuel Darkwah, Eiji Kawamoto, Eiji Kawamoto, Motomu Shimaoka   +8 more
doaj   +1 more source

Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice

Thrombosis Journal, 2023
Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu, Ying Zhou, Huihui Gao, Zeping Zhang, Yu Zhou, Zifeng Xu, Chenhong Zhang, Zhen Xu, Huajun Zheng, Yan-Qing Ma   +9 more
doaj   +1 more source