Results 31 to 40 of about 11,890,652 (305)
Altered Cell Adhesion and Glycosylation Promote Cancer Immune Suppression and Metastasis
Frontiers in Immunology, 2019 Cell-cell interactions and cell adhesion are key mediators of cancer progression and facilitate hallmarks of cancer including immune evasion and metastatic dissemination.
H. Läubli, L. Borsig
semanticscholar +1 more source
Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]
, 2002 In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
core +1 more source
The Evolution of Cell Adhesion [PDF]
The Journal of Cell Biology, 2000 Multicellular organisms clearly require mechanisms for intercellular communication and, perhaps even more basically, for intercellular cohesion. The most primitive sponges and coelenterates depend on cell adhesion for their organismal organization; so do insects, nematodes and vertebrates ...
Qi Zhao, Richard O. Hynes
openaire +3 more sources
Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis
Frontiers in Oncology, 2018 Metastasis is a multistep process in which tumor extracellular matrix (ECM) and cancer cell cytoskeleton interactions are pivotal. ECM is connected, through integrins, to the cell’s adhesome at cell–ECM adhesion sites and through them to the actin ...
V. Gkretsi, T. Stylianopoulos
semanticscholar +1 more source
MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis
Cells, 2023 Sepsis is a systemic inflammatory disorder that leads to the dysfunction of multiple organs. In the intestine, the deregulation of the epithelial barrier contributes to the development of sepsis by triggering continuous exposure to harmful factors ...
Siqingaowa Caidengbate +9 more
doaj +1 more source
Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Biomedicines, 2019 Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of this study is to shed light on the differential roles played by systemic versus mucosal DCs in ...
Samuel Darkwah +6 more
doaj +1 more source
Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Communications Biology, 2023 Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation.
Eva-Maria Thüring +9 more
doaj +1 more source
Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]
, 2016 Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir +7 more
core +1 more source
PI3K in T Cell Adhesion and Trafficking [PDF]
Frontiers in Immunology, 2021 PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of patients with Activated PI3K Delta Syndrome (APDS) and mouse models with hyperactive PI3Kδ have ...
Kristoffer H. Johansen +5 more
openaire +6 more sources
Cell adhesion is regulated by CDK1 during the cell cycle
Journal of Cell Biology, 2018 In most tissues, anchorage-dependent growth and cell cycle progression are dependent on cells engaging extracellular matrices (ECMs) via integrin–receptor adhesion complexes.
Matthew C. Jones +3 more
semanticscholar +1 more source