Cell Adhesion Molecules and Their Roles and Regulation in the Immune and Tumor Microenvironment
Frontiers in Immunology, 2019 The immune system and cancer have a complex relationship with the immune system playing a dual role in tumor development. The effector cells of the immune system can recognize and kill malignant cells while immune system-mediated inflammation can also ...
Heidi Harjunpää +3 more
semanticscholar +1 more source
A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence
Frontiers in Cellular Neuroscience, 2018 Understanding the mechanisms guiding interneuron development is a central aspect of the current research on cortical/hippocampal interneurons, which is highly relevant to brain function and pathology.
Sira A. Franchi +8 more
doaj +1 more source
Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment
iScience, 2022 Summary: Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell with resources derived from the internalized cell. Using
Mariel F. Schwietzer +8 more
doaj +1 more source
DISC1 regulates cell–cell adhesion, cell–matrix adhesion and neurite outgrowth [PDF]
Molecular Psychiatry, 2010 Disrupted-in-schizophrenia 1 (DISC1) is a promising susceptibility gene for major mental illness. Recent studies have implicated DISC1 in key neurodevelopmental processes, including neurite outgrowth, neuronal migration and proliferation. Here, we report that DISC1 regulates cell-cell and cell-matrix adhesion and neurite outgrowth. DISC1 overexpression
T, Hattori +9 more
openaire +2 more sources
Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]
, 2002 In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
core +1 more source
FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
Biomolecules, 2020 Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major driver of invasion and metastasis and its upregulation is associated with poor
Paula Tapial Martínez +2 more
doaj +1 more source
Emerging Roles of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Immunological Disorders and Cancer
International Journal of Molecular Sciences, 2018 Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules.
Deok-Hoon Kong +4 more
semanticscholar +1 more source
Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Biomedicines, 2019 Sepsis is a systemically dysregulated inflammatory syndrome, in which dendritic cells (DCs) play a critical role in coordinating aberrant immunity. The aim of this study is to shed light on the differential roles played by systemic versus mucosal DCs in ...
Samuel Darkwah +6 more
doaj +1 more source
Influence of cell surface characteristics on adhesion of Saccharomyces cerevisiae to the biomaterial hydroxylapatite [PDF]
, 2010 The influence of the physicochemical properties of biomaterials on microbial cell adhesion is well known, with the extent of adhesion depending on hydrophobicity, surface charge, specific functional groups and acid–base properties.
Walker, Graeme M., White, Jane S.
core +3 more sources