Results 41 to 50 of about 11,304,397 (389)

Rolling Cell Adhesion [PDF]

open access: yesAnnual Review of Cell and Developmental Biology, 2010
Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes, hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury. Rolling requires the rapid yet balanced formation and dissociation of adhesive bonds in the challenging environment of blood flow.
Cheng Zhu, Rodger P. McEver
openaire   +3 more sources

Ligand-competent fractalkine receptor is expressed on exosomes

open access: yesBiochemistry and Biophysics Reports, 2021
Expression of chemokine receptor CX3CR1 is reportedly restricted to several cell types including natural killer cells, cytotoxic T cells, monocytes, and macrophages.
Eun Jeong Park   +9 more
doaj  

The Role of Innate Lymphoid Cells in the Regulation of Immune Homeostasis in Sepsis-Mediated Lung Inflammation

open access: yesDiagnostics, 2020
Septic shock/severe sepsis is a deregulated host immune system response to infection that leads to life-threatening organ dysfunction. Lung inflammation as a form of acute lung injury (ALI) is often induced in septic shock.
Yuichi Akama   +7 more
doaj   +1 more source

Identification of a membrane-less compartment regulating invadosome function and motility

open access: yesScientific Reports, 2018
Depletion of liprin-α1, ERC1 or LL5 scaffolds inhibits extracellular matrix degradation by invasive cells. These proteins co-accumulate near invadosomes in NIH-Src cells, identifying a novel invadosome–associated compartment distinct from the core and ...
Kristyna Sala   +4 more
doaj   +1 more source

Synaptic Cell Adhesion [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2012
Chemical synapses are asymmetric intercellular junctions that mediate synaptic transmission. Synaptic junctions are organized by trans-synaptic cell adhesion molecules bridging the synaptic cleft. Synaptic cell adhesion molecules not only connect pre- and postsynaptic compartments, but also mediate trans-synaptic recognition and signaling processes ...
Thomas Biederer   +2 more
openaire   +2 more sources

In vitro Cell Migration, Invasion, and Adhesion Assays: From Cell Imaging to Data Analysis

open access: yesFront. Cell Dev. Biol., 2019
Cell migration is a key procedure involved in many biological processes including embryological development, tissue formation, immune defense or inflammation, and cancer progression.
J. Pijuan   +7 more
semanticscholar   +1 more source

Modelling non-local cell-cell adhesion: a multiscale approach [PDF]

open access: yesarXiv, 2023
Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a versatile multiscale approach to modelling a moving self-adhesive cell population that combines a careful ...
arxiv  

Effect of adhesion geometry and rigidity on cellular force distributions [PDF]

open access: yesPhys Rev Lett 103, 048101 (2009), 2009
The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion. We introduce a mechanical model that predicts cellular force distributions for cells adhering to adhesive patterns with different geometries and rigidities.
arxiv   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

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