The Evolution of Cell Adhesion [PDF]
Multicellular organisms clearly require mechanisms for intercellular communication and, perhaps even more basically, for intercellular cohesion. The most primitive sponges and coelenterates depend on cell adhesion for their organismal organization; so do insects, nematodes and vertebrates ...
Qi Zhao, Richard O. Hynes
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MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis
Sepsis is a systemic inflammatory disorder that leads to the dysfunction of multiple organs. In the intestine, the deregulation of the epithelial barrier contributes to the development of sepsis by triggering continuous exposure to harmful factors ...
Siqingaowa Caidengbate+9 more
doaj +1 more source
Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib expression is associated with disturbed apical-basal polarity and tumor formation.
Eva-Maria Thüring+9 more
doaj +1 more source
PI3K in T Cell Adhesion and Trafficking [PDF]
PI3K signalling is required for activation, differentiation, and trafficking of T cells. PI3Kδ, the dominant PI3K isoform in T cells, has been extensively characterised using PI3Kδ mutant mouse models and PI3K inhibitors. Furthermore, characterisation of patients with Activated PI3K Delta Syndrome (APDS) and mouse models with hyperactive PI3Kδ have ...
Kristoffer H. Johansen+5 more
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Influence of cell surface characteristics on adhesion of Saccharomyces cerevisiae to the biomaterial hydroxylapatite [PDF]
The influence of the physicochemical properties of biomaterials on microbial cell adhesion is well known, with the extent of adhesion depending on hydrophobicity, surface charge, specific functional groups and acid–base properties.
Walker, Graeme M., White, Jane S.
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Cell adhesion is regulated by CDK1 during the cell cycle
In most tissues, anchorage-dependent growth and cell cycle progression are dependent on cells engaging extracellular matrices (ECMs) via integrin–receptor adhesion complexes.
Matthew C. Jones+3 more
semanticscholar +1 more source
A Review of Cell Adhesion Studies for Biomedical and Biological Applications
Cell adhesion is essential in cell communication and regulation, and is of fundamental importance in the development and maintenance of tissues. The mechanical interactions between a cell and its extracellular matrix (ECM) can influence and control cell ...
Amelia Ahmad Khalili, M. Ahmad
semanticscholar +1 more source
Hydroxyapatite promotes superior adhesion and proliferation of telomerase transformed keratocytes in comparison with inert plastic skirt materials used in leading contemporary keratoprostheses [PDF]
Aim: Published clinical series suggest the osteoodontokeratoprosthesis (OOKP) may have a lower extrusion rate than current synthetic keratoprostheses. The OOKP is anchored in the eye wall by autologous tooth.
Allen, B.D.S.+6 more
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GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. [PDF]
Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous.
David James, C+11 more
core +1 more source
Polymorphism and bistability in adherent cells
The optimal shapes attained by contractile cells on adhesive substrates are determined by the interplay between intracellular forces and adhesion with the extracellular matrix.
Banerjee, Shiladitya, Giomi, Luca
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