Results 51 to 60 of about 805,424 (161)

The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer

open access: yesThe Scientific World Journal, 2010
Activation of Src family kinases is an important event downstream of integrin adhesion signaling in many cell types. A particularly intriguing connection between an integrin and a Src family kinase was first discovered in platelets, where the selective ...
Stephan Huveneers, Erik H. J. Danen
doaj   +1 more source

Spindle pole cohesion requires glycosylation-mediated localization of NuMA

open access: yesScientific Reports, 2017
Glycosylation is critical for the regulation of several cellular processes. One glycosylation pathway, the unusual O-linked β-N-acetylglucosamine glycosylation (O-GlcNAcylation) has been shown to be required for proper mitosis, likely through a subset of
Jérémy Magescas   +10 more
doaj   +1 more source

Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells

open access: yesNature Communications, 2017
Cancer cells can disrupt cell-to-cell junctions, thus allowing migration and metastasis. Here starting from a chemical screening, Ito et al. reconstitute a step-by-step mechanism linking microtubule depolymerization and epithelial cell junction ...
Shoko Ito   +6 more
doaj   +1 more source

Cell adhesion molecules [PDF]

open access: yesClinical Molecular Pathology, 1996
Freemont, A J, Hoyland, J A
openaire   +3 more sources

RhoGDI1 regulates cell-cell junctions in polarized epithelial cells

open access: yesFrontiers in Cell and Developmental Biology
Cell-cell contact formation of polarized epithelial cells is a multi-step process that involves the co-ordinated activities of Rho family small GTPases. Consistent with the central role of Rho GTPases, a number of Rho guanine nucleotide exchange factors (
Nicolina Wibbe   +13 more
doaj   +1 more source

Exploratory characterization of dynamic soluble programmed death-ligand 1 trajectories and their association with mortality in critical coronavirus disease 2019

open access: yesJournal of Intensive Care
Background Persistent immune checkpoint activation is a recognized feature of critical coronavirus disease 2019 (COVID-19). However, the temporal behavior and clinical utility of soluble programmed death-ligand 1 (sPD-L1) remain unclear.
Shungo Takeuchi   +8 more
doaj   +1 more source

Clinical Application of Clot Waveform Analysis

open access: yesClinical and Applied Thrombosis/Hemostasis
Clot waveform analysis (CWA) involves an analysis of the activated partial thromboplastin time (CWA-APTT), diluted prothrombin time (CWA-dPT), and small amount of thrombin time (CWA-sTT), and clot fibrinolysis waveform analysis (CFWA).
Hideo Wada MD, PhD   +5 more
doaj   +1 more source

Cell adhesion

open access: yesProgress in Biophysics and Molecular Biology, 1973
openaire   +2 more sources

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