Results 11 to 20 of about 767,177 (355)
Stick around: Cell–Cell Adhesion Molecules during Neocortical Development
The neocortex is an exquisitely organized structure achieved through complex cellular processes from the generation of neural cells to their integration into cortical circuits after complex migration processes. During this long journey, neural cells need
David de Agustín-Durán+3 more
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On the adhesion of vesicles by cell adhesion molecules [PDF]
This paper gives a detailed analysis of experiments on the kinetics of aggregation of lipid vesicles containing neural cell adhesion molecules (N-CAM). An explanation for the dependence of the "initial aggregation rate," kagg, on the square of the vesicle concentration is given, accounting both for Brownian motion of the vesicles and shear effects.
D.C. Torney, G.I. Bell
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Cell Adhesion Molecules in Normal Skin and Melanoma
Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin protein families are indispensable for the formation and maintenance of multicellular tissues, especially epithelia.
Cian D’Arcy, Christina Kiel
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Endothelial Cell Adhesion Molecules- (un)Attainable Targets for Nanomedicines
Endothelial cell adhesion molecules have long been proposed as promising targets in many pathologies. Despite promising preclinical data, several efforts to develop small molecule inhibitors or monoclonal antibodies (mAbs) against cell adhesion molecules
Nenad Milošević+2 more
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Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao+12 more
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Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]
In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
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Cell adhesion molecules in the CNS [PDF]
Cell-cell adhesions are important for brain morphology and highly coordinated brain functions such as memory and learning ([Sanes and Yamagata, 1999][1]; [Yamagata et al., 2003][2]; [Washbourne et al., 2004][3]).
Toshiaki Sakisaka, Yoshimi Takai
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Adhesion of membranes via receptor-ligand complexes: Domain formation, binding cooperativity, and active processes [PDF]
Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during adhesion, and ...
Albersdörfer+116 more
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The importance of selected cell adhesion molecules in thyroid cancer
Thyroid cancer is the most common malignant tumour of the endocrine system. It accounts for ca. 2% of all malignant tumours in the world, ranking it 16th in the overall classification. Its most common histology type is the papillary carcinoma originating
Magdalena Urbańczuk+5 more
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Re: Role of Telomeres and Telomerase in Cancer
The most important difference between cancer and normall cells is the ability to continuous proliferation. This activation works due to telomeres and telomerase enzyme.
Shay JW, Wright WE
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