Synaptic Cell Adhesion Molecules in Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative brain disorder associated with the loss of synapses between neurons in the brain. Synaptic cell adhesion molecules are cell surface glycoproteins which are expressed at the synaptic plasma membranes of ...
Iryna Leshchyns’ka, Vladimir Sytnyk
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Cadherins, Selectins, and Integrins in CAM-DR in Leukemia
The interaction between leukemia cells and the bone microenvironment is known to provide drug resistance in leukemia cells. This phenomenon, called cell adhesion-mediated drug resistance (CAM-DR), has been demonstrated in many subsets of leukemia ...
Hye Na Kim +4 more
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Alterations in Circulating Adhesion Molecules in Acute Myocardial Infarction before and after Thrombolysis with Streptokinase [PDF]
Introduction: The role of adhesion molecules in the development and progression of coronary atherosclerosis is inevitable. It is not clear yet whether these molecules increase or decrease in level after thrombolytic therapy.
Hossein Saidi +4 more
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Background & Aims: Aberrant lymphocyte homing could potentially link inflammatory processes in the intestine and the liver, as distinct hepatobiliary diseases frequently develop as extra-intestinal manifestations in inflammatory bowel disease.
Angela Schippers +10 more
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Vascular Cell Adhesion Molecule-1 Is a Key Adhesion Molecule in Melanoma Cell Adhesion to the Leptomeninges [PDF]
Leptomeningeal metastases occur in up to 8% of patients with systemic malignancies and have a poor prognosis. A better understanding of the pathophysiologic processes underlying leptomeningeal metastases is needed for more effective treatment strategies.
Dieta, Brandsma +7 more
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Acoustic Force-Based Cell–Matrix Avidity Measurement in High Throughput
Cancer cells interacting with the extracellular matrix (ECM) in the tumor microenvironment is pivotal for tumorigenesis, invasion, and metastasis. Cell–ECM adhesion has been intensively studied in cancer biology in the past decades to understand the ...
Yao Wang +3 more
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A parallel-plate flow chamber to study initial cell adhesion on a nanofeatured surface [PDF]
Cells in the human body come across many types of information, which they respond to. Both material chemistry and topography of the surface where they adhere have an effect on cell shape, proliferation, migration, and gene expression.
K. McGhee +7 more
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Cell Adhesion Molecules in Neuroblastoma: Complex Roles, Therapeutic Potential
Neuroblastoma, a biologically heterogeneous tumor derived from neural crest cells, accounts for approximately 15% of childhood deaths from cancer.
Briana E. Heinly +2 more
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Cell Adhesion Molecules and the Bronchial Epithelium [PDF]
Abstract The bronchial epithelium is the major barrier between the host and the provoking antigens in bronchial asthma. Recent studies have indicated that the epithelium is a truly stratified structure, with the superficial columnar cells depending on the underlying basal cells for anchorage.
Roche, William R. +3 more
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Increasing throughput of AFM-based single cell adhesion measurements through multisubstrate surfaces
Mammalian cells regulate adhesion by expressing and regulating a diverse array of cell adhesion molecules on their cell surfaces. Since different cell types express distinct sets of cell adhesion molecules, substrate-specific adhesion is cell type- and ...
Miao Yu +4 more
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