Biomolecules, 2021 Pemphigus and pemphigoid diseases are potentially life-threatening autoimmune blistering disorders that are characterized by intraepithelial and subepithelial blister formation, respectively. In both disease groups, skin and/or mucosal blistering develop
Nicola Cirillo, Stephen S. Prime
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Cadherin composition and multicellular aggregate invasion in organotypic models of epithelial ovarian cancer intraperitoneal metastasis. [PDF]
, 2017 During epithelial ovarian cancer (EOC) progression, intraperitoneally disseminating tumor cells and multicellular aggregates (MCAs) present in ascites fluid adhere to the peritoneum and induce retraction of the peritoneal mesothelial monolayer prior to ...
Alber, M +6 more
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Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. [PDF]
, 2018 Visual information is delivered to the brain by >40 types of retinal ganglion cells (RGCs). Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of each RGC type are restricted to specific sublaminae ...
Chen, Bin +7 more
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Interplay of Eph-Ephrin Signalling and Cadherin Function in Cell Segregation and Boundary Formation
Frontiers in Cell and Developmental Biology, 2021 The segregation of distinct cell populations to form sharp boundaries is crucial for stabilising tissue organisation, for example during hindbrain segmentation in craniofacial development.
David G. Wilkinson
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Dental Research JournalBackground: Accurate and early diagnosis of dysplastic lesions is crucial for successful treatment. A decrease in E-cadherin expression has been observed in dysplastic lesions and tumors. Therefore, the aim of this study was to investigate the expression
Laleh Maleki +3 more
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Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt
Biomolecular Concepts, 2015 Both cell-cell and cell-matrix adhesion are important for epithelial cell differentiation and function. Classical cadherins mediate cell to cell interactions and are potent activators of the signal transducer and activator of transcription (Stat3 ...
Niit Maximilian +6 more
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Frontiers in Molecular Neuroscience, 2021 Type I and type II classical cadherins comprise a family of cell adhesion molecules that regulate cell sorting and tissue separation by forming specific homo and heterophilic bonds.
Julie Polanco +4 more
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T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo [PDF]
, 1991 Trunk neural crest cells and motor axons move in a segmental fashion through the rostral (anterior) half of each somitic sclerotome, avoiding the caudal (posterior) half.
Bronner-Fraser, Marianne +1 more
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Genomic alterations in primary gastric adenocarcinomas correlate with clinicopathological characteristics and survival. [PDF]
, 2004 Background & aimsPathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at the chromosomal level. In order to investigate the patterns of chromosomal aberrations in gastric carcinomas, we performed
Albertson, Donna +7 more
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Downregulation of Fzd6 and Cthrc1 and upregulation of olfactory receptors and protocadherins by dietary beta-carotene in lungs of Bcmo1-/- mice. [PDF]
, 2010 An ongoing controversy exists on beneficial versus harmful effects of high beta-carotene (BC) intake, especially for the lung. To elucidate potential mechanisms, we studied effects of BC on lung gene expression.
Amengual, J. +9 more
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