Results 41 to 50 of about 28,625 (255)

Cadherins and epithelial-to-mesenchymal transition

open access: yes, 2013
Epithelial–mesenchymal transition (EMT) is a process whereby epithelial cells are transcriptionally reprogrammed, resulting in decreased adhesion and enhanced migration or invasion.
Alexander Gheldof   +3 more
core   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

open access: yesAdvanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim   +7 more
wiley   +1 more source

Doctor of Philosophy [PDF]

open access: yes, 2017
dissertationSingle neurons often receive synapses with distinct properties. However, the molecules regulating these distinct properties remain largely unknown. This dissertation focuses on deciphering such molecules using the mammalian hippocampus as the
Basu, Raunak
core  

Adhesion Molecules. I: Keratinocyte-Keratinocyte Interactions; Cadherins and Pemphigus

open access: yes, 1995
During the last few years, considerable progress has been made in our understanding of the structure and function of cadherins and of the pathophysiology of pemphigus.
Amagai, Masayuki
core   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

open access: yesAdvanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett   +15 more
wiley   +1 more source

Role of Cadherins in Cancer—A Review

open access: yes, 2020
Cadherins play an important role in tissue homeostasis, as they are responsible for cell-cell adhesion during embryogenesis, tissue morphogenesis, differentiation and carcinogenesis.
Bożena Dworecka-Kaszak   +5 more
core   +1 more source

Retinal cadherins and the retinal cadherinopathies: current concepts and future directions

open access: yes, 2022
Cadherins are a superfamily of calcium-dependent intercellular adhesion molecules that are widely expressed in living tissues. Within the retina and retinal pigment epithelium (RPE), cadherins contribute to tissue morphogenesis, neural circuit formation,
Garrett, Andrew   +3 more
core   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

open access: yesAdvanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa   +8 more
wiley   +1 more source

Cadherin specificity in adhesion and mechanotransduction

open access: yes, 2009
Cadherins mediate Ca2+ dependent cell-cell junction in all animal tissues. Tight regulation of cadherin adhesion plays critical roles in diverse biological processes.
Shi, Quanming
core  

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

open access: yesAdvanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim   +5 more
wiley   +1 more source

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