Results 21 to 30 of about 26,522 (261)

Impact of Ki-67 and E-cadherin expression on lymphovascular invasion in upper urinary tract urothelial carcinoma [PDF]

Vojnosanitetski Pregled, 2015
Bacground/Aim. Upper urinary tract urothelial carcinoma (UUT-UC) constitutes 5% of malignant neoplasms arising from transitional epithelium, but is more invasive than bladder cancer.
Stojnev Slavica, Krstić Miljan, Janković-Veličković Ljubinka, Ristić-Petrović Ana, Milojković Maja, Jovanović Ivan, Stokanović Dragana, Ugrenović Slađana   +7 more
doaj   +1 more source

Computer simulations of cell sorting due to differential adhesion.

PLoS ONE, 2011
The actions of cell adhesion molecules, in particular, cadherins during embryonic development and morphogenesis more generally, regulate many aspects of cellular interactions, regulation and signaling.
Ying Zhang, Gilberto L Thomas, Maciej Swat, Abbas Shirinifard, James A Glazier   +4 more
doaj   +1 more source

Interplay between integrins and cadherins to control bone differentiation upon BMP-2 stimulation

Frontiers in Cell and Developmental Biology, 2023
Introduction: Upon BMP-2 stimulation, the osteoblastic lineage commitment in C2C12 myoblasts is associated with a microenvironmental change that occurs over several days.
Anne Valat, Laure Fourel, Adria Sales, Paul Machillot, Paul Machillot, Anne-Pascale Bouin, Carole Fournier, Lauriane Bosc, Mélanie Arboléas, Ingrid Bourrin-Reynard, Amy J. Wagoner Johnson, Amy J. Wagoner Johnson, Amy J. Wagoner Johnson, Amy J. Wagoner Johnson, Franz Bruckert, Corinne Albigès-Rizo, Catherine Picart, Catherine Picart, Catherine Picart   +18 more
doaj   +1 more source

P-, E-, and H-cadherins differ in their relationships with coronary stenosis, cardiovascular outcomes, and unplanned recurrent revascularization

Journal of Molecular and Cellular Cardiology Plus
Background and aims: Cadherins are adhesion proteins, and their dysregulation may result in the development of atherosclerosis, plaque rupture, or lesions of the vascular wall.
Nadezhda G. Gumanova, Dmitry K. Vasilyev, Natalya L. Bogdanova, Yaroslav I. Havrichenko, Oxana M. Drapkina   +4 more
doaj   +1 more source

“Switch of E-Cadherin to N-Cadherin expression in different molecular subtypes of breast invasive duct carcinomas and its correlation with clinicopathological features”

Indian Journal of Pathology and Microbiology, 2021
Background: In breast cancer, metastasis and recurrence is the main culprit in treatment failure. This study aimed to explore the role of E-cadherin/N-cadherin Switch in progression, spread and metastasis in breast invasive duct carcinoma.
Mayada S Farrag, Abeer H Anter, Nesrine S Farrag, Afaf T Ibrahiem   +3 more
doaj   +1 more source

A Scoping Review of the Role of Metalloproteinases in the Pathogenesis of Autoimmune Pemphigus and Pemphigoid

Biomolecules, 2021
Pemphigus and pemphigoid diseases are potentially life-threatening autoimmune blistering disorders that are characterized by intraepithelial and subepithelial blister formation, respectively. In both disease groups, skin and/or mucosal blistering develop
Nicola Cirillo, Stephen S. Prime
doaj   +1 more source

Anticancer Activity of Holothuria Leucospilota-Derived Saponin on MKN45 Gastric Cancer Cell via Upregulation of CDH1 Hub Gene [PDF]

Middle East Journal of Cancer
Background: The treatment of gastric cancer (GC) is still quite challenging. Yet, marine invertebrates have been found to produce a wide range of anticancer bioactive compounds that show promise in fighting cancer.
Khadijeh Sadegh, Amirhossein Ahmadi, Ahmad Shadi, Ahmad Ghasemi   +3 more
doaj   +1 more source

E-cadherin binds to desmoglein to facilitate desmosome assembly

eLife, 2018
Desmosomes are adhesive junctions composed of two desmosomal cadherins: desmocollin (Dsc) and desmoglein (Dsg). Previous studies demonstrate that E-cadherin (Ecad), an adhesive protein that interacts in both trans (between opposing cells) and cis (on the
Omer Shafraz, Matthias Rübsam, Sara N Stahley, Amber L Caldara, Andrew P Kowalczyk, Carien M Niessen, Sanjeevi Sivasankar   +6 more
doaj   +1 more source

Cadherin Expression and EMT: A Focus on Gliomas

Biomedicines, 2021
Cadherins are calcium-binding proteins with a pivotal role in cell adhesion and tissue homeostasis. The cadherin-dependent mechanisms of cell adhesion and migration are exploited by cancer cells, contributing to tumor invasiveness and dissemination.
Carolina Noronha, Ana Sofia Ribeiro, Ricardo Taipa, Diogo S. Castro, Joaquim Reis, Cláudia Faria, Joana Paredes   +6 more
doaj   +1 more source

Holding it together: when cadherin meets cadherin

Biophysical Journal, 2021
Intercellular adhesion is the key to multicellularity, and its malfunction plays an important role in various developmental and disease-related processes. Although it has been intensively studied by both biologists and physicists, a commonly accepted definition of cell-cell adhesion is still being debated.
Arslan, F.N., Eckert, J., Schmidt, T., Heisenberg, C.P.   +3 more
openaire   +5 more sources