Results 11 to 20 of about 26,522 (261)
Design of a Photoswitchable Cadherin [PDF]
Journal of the American Chemical Society, 2013 There is a growing interest in engineering proteins whose function can be controlled with the spatial and temporal precision of light. Here, we present a novel example of a functional light-triggered switch in the Ca-dependent cell-cell adhesion protein E-cadherin, created using a mechanism-based design strategy. We report an 18-fold change in apparent
Kortemme, Tanja +3 more
openaire +4 more sources
Expression of classic cadherins and δ-protocadherins in the developing ferret retina
BMC Neuroscience, 2009 Background Cadherins are a superfamily of calcium-dependent adhesion molecules that play multiple roles in morphogenesis, including proliferation, migration, differentiation and cell-cell recognition.
Krishna-K K +2 more
doaj +1 more source
Pathogens, 2023 Trichomonas vaginalis is an extracellular protozoan parasite that causes human trichomoniasis, a sexually transmitted infection (STI) that affects approximately 270 million people worldwide. The phenomenon of T. vaginalis adhesion to inert substrates has
Sharmila Fiama das Neves Ortiz +3 more
doaj +1 more source
Restricted expression of classic cadherins in the spinal cord of the chicken embryo
Frontiers in Neuroanatomy, 2014 Classic cadherins belong to the family of cadherin genes and play important roles in neurogenesis, neuron migration and axon growth. In the present study, we compared the expression patterns of 10 classic cadherins (Cdh2, Cdh4, Cdh6, Cdh7, Cdh8, Cdh9 ...
Juntang eLin +4 more
doaj +1 more source
Evolutionary origin of type IV classical cadherins in arthropods
BMC Evolutionary Biology, 2017 Background Classical cadherins are a metazoan-specific family of homophilic cell-cell adhesion molecules that regulate morphogenesis. Type I and type IV cadherins in this family function at adherens junctions in the major epithelial tissues of ...
Mizuki Sasaki +2 more
doaj +1 more source
Cadherin Signaling in Cancer: Its Functions and Role as a Therapeutic Target
Frontiers in Oncology, 2019 Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and differentiation throughout life.
Weina Yu +12 more
doaj +1 more source
Adhesion molecules in Wilms tumor (part I) [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2003 Adhesion molekues are glicoprotees which have extracellular, transmembranous and intracytoplasmatic part. They show their basic role is in cell interaction in the tissue on one side and between cells and matrix on the other side.
Basta-Jovanović Gordana M. +2 more
doaj +1 more source
The cadherin superfamily [PDF]
WormBook, 2005 The cadherins are a major class of membrane proteins with prominent roles in cell adhesion, and the regulation of tissue organisation and morphogenesis. The C. elegans genome encodes 13 cadherins, including representatives of the major cadherin sub-types that are conserved between insects and vertebrates: the so-called classic, Fat-like, Flamingo and ...
openaire +2 more sources
The role of the cell adhesion molecules (integrins / cadherins) in prostate cancer
International Brazilian Journal of Urology, 2011 During prostate carcinogenesis the cellular adhesion molecules, i.e.; integrins and cadherins mediate aberrant interactions between glandular epithelial cells and the extracellular matrix. Several integrin α subunits are down-regulated, while β
Alexandros Drivalos +4 more
doaj +1 more source
Cell Adhesion Molecules in Normal Skin and Melanoma
Biomolecules, 2021 Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin protein families are indispensable for the formation and maintenance of multicellular tissues, especially epithelia.
Cian D’Arcy, Christina Kiel
doaj +1 more source