Results 21 to 30 of about 788,026 (349)

Cell Adhesion Molecules in Normal Skin and Melanoma

open access: yesBiomolecules, 2021
Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin protein families are indispensable for the formation and maintenance of multicellular tissues, especially epithelia.
Cian D’Arcy, Christina Kiel
doaj   +1 more source

Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1

open access: yesCell Communication and Signaling, 2019
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao   +12 more
doaj   +1 more source

Adhesion of membranes via receptor-ligand complexes: Domain formation, binding cooperativity, and active processes [PDF]

open access: yes, 2009
Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during adhesion, and ...
Albersdörfer   +116 more
core   +2 more sources

Animal lectins as cell adhesion molecules [PDF]

open access: yes, 1998
Protein-carbohydrate interaction is exploited in cell adhesion mechanisms besides the recognition of peptide motifs. The sugar code thus significantly contributes to the intriguing specificity of cellular selection of binding partners.
Kaltner, H., Stierstorfer, B.
core   +1 more source

The importance of selected cell adhesion molecules in thyroid cancer

open access: yesJournal of Education, Health and Sport, 2018
Thyroid cancer is the most common malignant tumour of the endocrine system. It accounts for ca. 2% of all malignant tumours in the world, ranking it 16th in the overall classification. Its most common histology type is the papillary carcinoma originating
Magdalena Urbańczuk   +5 more
doaj   +3 more sources

Re: Role of Telomeres and Telomerase in Cancer

open access: yesJournal of Urological Surgery, 2016
The most important difference between cancer and normall cells is the ability to continuous proliferation. This activation works due to telomeres and telomerase enzyme.
Shay JW, Wright WE
doaj   +1 more source

Melanoma-associated adhesion molecule MUC18/MCAM (CD146) and transcriptional regulator Mader in normal human CNS [PDF]

open access: yes, 1998
The proteins MUC18 and Mader have been identified as markers of tumor progression in melanoma cells, MUC18, also known as MCAM (melanoma cell adhesion molecule) and as CD146 (endothelial antigen), is a cell adhesion molecule belonging to the ...
Ackenheil, Manfred   +7 more
core   +1 more source

Cell adhesion molecules in the pathogenesis of the schizophrenia [PDF]

open access: yesFolia Medica, 2023
The causes of schizophrenia remain obscure and complex to identify. Alterations in dopaminergic and serotonergic neurotransmission are, to date, the primary pharmacological targets in treatment.
Antonino Messina   +4 more
doaj   +3 more sources

The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules [PDF]

open access: yes, 2016
Multicellular organisms rely on cell adhesion molecules to coordinate cell–cell interactions, and to provide navigational cues during tissue formation.
Davies, Shireen-Anne   +7 more
core   +2 more sources

Reciprocal interactions between cell adhesion molecules of the immunoglobulin superfamily and the cytoskeleton in neurons

open access: yesFrontiers in Cell and Developmental Biology, 2016
Cell adhesion molecules of the immunoglobulin superfamily (IgSF) including the neural cell adhesion molecule (NCAM) and members of the L1 family of neuronal cell adhesion molecules play important functions in the developing nervous system by regulating ...
Vladimir eSytnyk, Iryna eLeshchyns'Ka
doaj   +1 more source

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