Results 1 to 10 of about 498,181 (163)

Dual implication of endothelial adhesion molecules in tumor progression and cancer immunity [PDF]

open access: yesCell Adhesion & Migration
Adhesion molecules are proteins expressed at the surface of various cell types. Their main contribution to immunity is to allow the infiltration of immune cells in an inflamed site.
Louis-Emmanuel Chriqui   +2 more
doaj   +2 more sources

Circulating cell adhesion molecules in systemic sclerosis: a systematic review and meta-analysis [PDF]

open access: yesFrontiers in Immunology
IntroductionPatients with systemic sclerosis (SSc) have an increased risk of endothelial dysfunction, atherosclerosis, and cardiovascular events compared to the general population.
Arduino A. Mangoni   +2 more
doaj   +2 more sources

Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice

open access: yesThrombosis Journal, 2023
Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu   +9 more
doaj   +1 more source

Adhesion molecules: a way to understand lupus

open access: yesRheumatology, 2022
Systemic lupus erythematosus is a connective disease in which all vitally important organs may be affected. The etiology of the disease is largely unknown and almost all immunological mechanisms have been proposed as the pathophysiological background of ...
Karolina Nowak   +2 more
doaj   +1 more source

The adhesion molecules of inflammation [PDF]

open access: yesArthritis & Rheumatism, 1993
BRUCE N. CRONSTEIN and GERALD WEISSMANN Inflammation is characterized by the accumula- tion of leukocytes and other mesenchymal cells at sites of injury or infection. When inflammation results from invasion by a microorganism, the inflammatory re- sponse is designed to localize, destroy, and eliminate the offending organism. However, persistent inflam-
B N, Cronstein, G, Weissmann
openaire   +2 more sources

Adhesion molecules and pancreatitis [PDF]

open access: yesJournal of Gastroenterology, 2018
Acute and chronic pancreatitises are gastrointestinal inflammatory diseases, the incidence of which is increasing worldwide. Most (~ 80%) acute pancreatitis (AP) patients have mild disease, and about 20% have severe disease, which causes multiple organ failure and has a high mortality rate.
Sato, Takeshi   +2 more
openaire   +2 more sources

Cell Adhesion Molecules in Fibrotic Diseases

open access: yesBiomedicines, 2023
Mechanisms underlying the pathogenesis of tissue fibrosis remain incompletely understood. Emerging evidence suggests that cell adhesion molecules (CAMs) are critical in fibrotic progression in many organs, including lung, kidney, skin, and liver.
Qianjiang Hu   +5 more
doaj   +1 more source

Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1

open access: yesCell Communication and Signaling, 2019
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao   +12 more
doaj   +1 more source

Demystified ... adhesion molecules. [PDF]

open access: yesMolecular Pathology, 1998
The cell adhesion molecules are ubiquitous recognition molecules that allow cells to communicate with one another and their environment. Through these molecules, complex alterations in the cytoplasmic messenger pathways and the microfilamentous cytoskeleton can lead to profound alterations in cell division, differentiation, behaviour, and function (fig
openaire   +3 more sources

VCAM-1 and ICAM-1 serum levels as markers of relapse in visceral leishmaniasis

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2017
Objectives-Methods. Visceral leishmaniasis (VL) is characterized by chronicity and relapses despite efficacious treatment. Acute and chronic inflammatory processes and concomitant disturbances in cell adhesion characterize the pathogenesis of the disease.
Alexandros Makis   +5 more
doaj   +1 more source

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