Dual implication of endothelial adhesion molecules in tumor progression and cancer immunity [PDF]
Adhesion molecules are proteins expressed at the surface of various cell types. Their main contribution to immunity is to allow the infiltration of immune cells in an inflamed site.
Louis-Emmanuel Chriqui +2 more
doaj +3 more sources
Neural cell adhesion molecules
Adhesion molecules are expressed on the surface of various cells and establish cell-cell interaction, playing important roles in development, inflammatory reaction, immune response, and tissue regeneration.
B Anlar
doaj +3 more sources
Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice
Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu +9 more
doaj +1 more source
Adhesion molecules: a way to understand lupus
Systemic lupus erythematosus is a connective disease in which all vitally important organs may be affected. The etiology of the disease is largely unknown and almost all immunological mechanisms have been proposed as the pathophysiological background of ...
Karolina Nowak +2 more
doaj +1 more source
Mycophenolate mofetil inhibits lymphocyte binding and the upregulation of adhesion molecules in acute rejection of rat kidney allografts. [PDF]
Mycophenolate mofetil (MMF) interacts with purine metabolism and possibly with the expression of adhesion molecules. In the present study, we analysed the expression of these molecules in transplanted kidney allografts treated with RS LBNF1 kidneys were ...
Tilney, N. +5 more
core +2 more sources
Cell Adhesion Molecules in Fibrotic Diseases
Mechanisms underlying the pathogenesis of tissue fibrosis remain incompletely understood. Emerging evidence suggests that cell adhesion molecules (CAMs) are critical in fibrotic progression in many organs, including lung, kidney, skin, and liver.
Qianjiang Hu +5 more
doaj +1 more source
Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao +12 more
doaj +1 more source
Identification and characterization of cell adhesion molecules controlling synapse stability [PDF]
Neuronal circuits form the basis of a functional nervous system to process and integrate information and to react to environmental cues. The formation of functional synaptic connections between neurons is essential for the establishment of these circuits.
Enneking, Eva-Maria
core +1 more source
Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]
Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Lederer, Stephan R. +5 more
core +1 more source
VCAM-1 and ICAM-1 serum levels as markers of relapse in visceral leishmaniasis
Objectives-Methods. Visceral leishmaniasis (VL) is characterized by chronicity and relapses despite efficacious treatment. Acute and chronic inflammatory processes and concomitant disturbances in cell adhesion characterize the pathogenesis of the disease.
Alexandros Makis +5 more
doaj +1 more source

