Results 11 to 20 of about 475,866 (256)
Endothelial Cell Adhesion Molecules- (un)Attainable Targets for Nanomedicines
Frontiers in Medical Technology, 2022 Endothelial cell adhesion molecules have long been proposed as promising targets in many pathologies. Despite promising preclinical data, several efforts to develop small molecule inhibitors or monoclonal antibodies (mAbs) against cell adhesion molecules
Nenad Milošević +2 more
doaj +1 more source
Cell Adhesion Molecules in Normal Skin and Melanoma
Biomolecules, 2021 Cell adhesion molecules (CAMs) of the cadherin, integrin, immunoglobulin, and selectin protein families are indispensable for the formation and maintenance of multicellular tissues, especially epithelia.
Cian D’Arcy, Christina Kiel
doaj +1 more source
Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Cell Communication and Signaling, 2019 Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao +12 more
doaj +1 more source
The importance of selected cell adhesion molecules in thyroid cancer
Journal of Education, Health and Sport, 2018 Thyroid cancer is the most common malignant tumour of the endocrine system. It accounts for ca. 2% of all malignant tumours in the world, ranking it 16th in the overall classification. Its most common histology type is the papillary carcinoma originating
Magdalena Urbańczuk +5 more
doaj +3 more sources
Re: Role of Telomeres and Telomerase in Cancer
Journal of Urological Surgery, 2016 The most important difference between cancer and normall cells is the ability to continuous proliferation. This activation works due to telomeres and telomerase enzyme.
Shay JW, Wright WE
doaj +1 more source
Cell adhesion molecules in the pathogenesis of the schizophrenia [PDF]
Folia Medica, 2023 The causes of schizophrenia remain obscure and complex to identify. Alterations in dopaminergic and serotonergic neurotransmission are, to date, the primary pharmacological targets in treatment.
Antonino Messina +4 more
doaj +3 more sources
On the adhesion of vesicles by cell adhesion molecules
Biophysical Journal, 1985 This paper gives a detailed analysis of experiments on the kinetics of aggregation of lipid vesicles containing neural cell adhesion molecules (N-CAM). An explanation for the dependence of the "initial aggregation rate," kagg, on the square of the vesicle concentration is given, accounting both for Brownian motion of the vesicles and shear effects.
Bell, G.I., Torney, D.C.
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2016 Cell adhesion molecules of the immunoglobulin superfamily (IgSF) including the neural cell adhesion molecule (NCAM) and members of the L1 family of neuronal cell adhesion molecules play important functions in the developing nervous system by regulating ...
Vladimir eSytnyk, Iryna eLeshchyns'Ka
doaj +1 more source
Perinatal Inflammation: Could Partial Blocking of Cell Adhesion Molecule Function Be a Solution?
Children, 2021 In spite of the great advances made in recent years in prenatal and perinatal medicine, inflammation can still frequently result in injury to vital organs and often constitutes a major cause of morbidity.
Nikolaos Vrachnis +9 more
doaj +1 more source
Adhesion and proliferation of living cell on surface functionalized with glycine nanostructures
Nano Select, 2022 This research presents the application of glycine amino acid for establishing firm cell‐substrate interaction instead of expensive adhesion proteins, peptides and peptide derivatives.
Aminur Rahman +10 more
doaj +1 more source