Optimized Prostate Cancer Stage Classification Using XGBoost Based on Racial miRNA Expression. [PDF]
Syechlo J +7 more
europepmc +1 more source
Simulation-based active cell balancing of a four-cell lithium-ion pack using a Cuk converter and fuzzy-PID current control [PDF]
Tulu Megersa Lammecha +2 more
openalex +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
AxialTAD: an axial contrast architecture for TAD boundary prediction from Hi-C. [PDF]
Choi WY, Rhee JK.
europepmc +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Robust cis-by-trans epistasis in the human plasma proteome highlights an ABO-centered interaction network. [PDF]
Li J, Liu X.
europepmc +1 more source
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Evidence for balancing selection on loci associated with host use in the genome of a generalist plant parasite. [PDF]
Calvert M +4 more
europepmc +1 more source

