Results 221 to 230 of about 5,639,145 (346)
A multi-ethnic reference map of T cell receptor germline diversity reveals evidence of natural selection on alpha chain genes. [PDF]
Mantena S +4 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Toward engineered microbial chassis for growth-production balancing. [PDF]
Xia H, Wang B, Qi F, Huang J.
europepmc +1 more source
Dynamic flux balance analysis of cancer metabolism using expression-based human cell line models [PDF]
Liam P. Kelley +5 more
openalex +1 more source
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
IkappaBzeta in immune cells controls Th17-Th1 balance in imiquimod-induced psoriasis models [PDF]
Yusuke Inada +4 more
openalex +1 more source

