Results 11 to 20 of about 3,538,937 (352)
Cultured normal human and animal cells are predestinued to undergo irreversible functional decrements that mimick age changes in the whole organism. When normal human embryonic fibroblasts are cultured in vitro, 50 +/- 10 population doublings occur.
Leonard Hayflick
openaire +6 more sources
The cell biology of smell [PDF]
The olfactory system detects and discriminates myriad chemical structures across a wide range of concentrations. To meet this task, the system utilizes a large family of G protein–coupled receptors—the odorant receptors—which are the chemical sensors underlying the perception of smell.
DeMaria, Shannon, Ngai, John
openaire +5 more sources
As with the experimental sciences, the cell simulation field is largely driven by the development of new techniques, and of new tools that implement those techniques. Many techniques under development are working to increase simulation accuracy while reducing the computational burden.
Steven S. Andrews+2 more
openaire +3 more sources
How does the nucleus move within the cell? How is the nucleus compartmentalized? How is nuclear size maintained? How is chromatin organized within the nucleus? These are a few of the questions related to nuclear cell biology addressed by our Minisymposium. Dan Starr led off with a description of how nuclei migrate in Caenorhabditis elegans.
Pombo, A., Starr, D.A.
openaire +3 more sources
Close-up on cell biology [PDF]
To define the workings of cellular structures and molecules requires cutting-edge technology not only in biology and biochemistry, but also now in nanotechnology. Hayley M. Birch and Julie Clayton report.
Julie Clayton, Hayley M. Birch
openaire +3 more sources
The past decade has revealed the diversity and ubiquity of archaea in nature, with a growing number of studies highlighting their importance in ecology, biotechnology and even human health. Myriad lineages have been discovered, which expanded the phylogenetic breadth of archaea and revealed their central role in the evolutionary origins of eukaryotes ...
Marleen van Wolferen+4 more
openaire +3 more sources
Cell biology beyond the cell [PDF]
This issue of the JCB marks the start of a new series of reviews entitled “The Cell Biology of…”. The goal of this series is to elucidate the cell biology underlying complex physiological processes.
Tom Misteli, Priya Prakash Budde
openaire +3 more sources
Summary: The DNA-damage response is a complex signaling network that guards genomic integrity. The microtubule cytoskeleton is involved in the repair of DNA double-strand breaks; however, little is known about which cytoskeleton-related proteins are ...
Arlinda Dullovi+6 more
doaj +1 more source
NaNog: A pluripotency homeobox (master) molecule. [PDF]
One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE+4 more
core +1 more source
Cell Biology of the Mitochondrion [PDF]
AbstractMitochondria are best known for harboring pathways involved in ATP synthesis through the tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding these roles were made with Caenorhabditiselegans mutants affecting key components of the metabolic pathways.
van der Bliek, Alexander M+2 more
openaire +5 more sources