Results 31 to 40 of about 3,610,600 (306)
GDF5 induces TBX3 in a concentration dependent manner - on a gold nanoparticle gradient
Organs and tissues, such as cartilage and limbs, are formed during development through an orchestration of growth factors that function as morphogens.
L. Andreasson +2 more
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Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]
Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley +108 more
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Cell biology beyond the cell [PDF]
This issue of the JCB marks the start of a new series of reviews entitled “The Cell Biology of…”. The goal of this series is to elucidate the cell biology underlying complex physiological processes.
Budde, Priya Prakash, Misteli, Tom
openaire +2 more sources
Global parameter identification of stochastic reaction networks from single trajectories [PDF]
We consider the problem of inferring the unknown parameters of a stochastic biochemical network model from a single measured time-course of the concentration of some of the involved species.
A Auger +38 more
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Cell biology of CML cells [PDF]
At the cellular level, expansion of haemopoiesis in chronic myeloid leukaemia (CML) must involve some imbalance in cell production along the myeloid maturation pathway. The relevant kinetic parameters are cell loss by apoptosis and differentiation and cell gain by proliferation (self-renewal).
Gordon, M. Y. +7 more
openaire +2 more sources
Give me a SINE: how Selective Inhibitors of Nuclear Export modulate autophagy and aging
Autophagy is a cellular recycling process leading to lysosomal degradation of damaged macromolecules, which can protect cells against aging. The transcription factor EB (TFEB), a major transcriptional regulator of genes involved in autophagy and ...
A.V. Kumar +5 more
doaj +1 more source
Cancer is becoming the leading cause of death all around the world. To develop better therapeutic options against cancer, we need a thorough understanding of tumor development and dissemination. As our knowledge increases, it becomes apparent that cancer
Serkan İsmail Göktuna +2 more
doaj +1 more source
Summary: Centrosomal protein 120 (CEP120) is a 120 kDa centrosome protein that plays an important role in centrosome replication. Overexpression of CEP120 can lead to centrosome duplicate abnormality, which is closely associated with tumorigenesis and ...
Chenggang Zhang +11 more
doaj +1 more source
mRNA splicing is modulated by intronic microRNAs
Summary: Splicing of transcripts is catalyzed by the spliceosome, a mega-complex consisting of hundreds of proteins and five snRNAs, which employs direct interactions. When U1 snRNA forms high-affinity binding, namely more than eight base pairs, with the
Luba Farberov +7 more
doaj +1 more source
Cell biology, SevERing mitochondria
The endoplasmic reticulum is an active participant in the division of another organelle, the ...
Lippincott-Schwarz, J., Rambold, A.
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