Results 31 to 40 of about 8,046,202 (313)

Cell Biology of the Mitochondrion [PDF]

Genetics, 2017
AbstractMitochondria are best known for harboring pathways involved in ATP synthesis through the tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding these roles were made with Caenorhabditiselegans mutants affecting key components of the metabolic pathways.
van der Bliek, Alexander M, Sedensky, Margaret M, Morgan, Phil G   +2 more
openaire   +4 more sources

Phosphorylation controls autoinhibition of cytoplasmic linker protein-170 [PDF]

, 2010
Author Posting. © American Society for Cell Biology, 2010. This article is posted here by permission of American Society for Cell Biology for personal use, not for redistribution. The definitive version was published in Molecular Biology of the Cell 21
Lee, Ho-Sup, Jeffrey van Haren, Schober, J.M. (Joseph), Borisy, G.G. (Gary), Ho-sup Lee, Komarova, Y. (Yulia), John G. Peloquin, Borisy, Gary G, Danciu, O. (Oana), Nadezhdina, Elena S., van Haren, Jeffrey, Gary G. Borisy, Steven P. Gygi, Akhmanova, A.S. (Anna), van Haren, Jeffrey; id_orcid, Peloquin, J.G. (John), Galjart, Niels; id_orcid, Niels Galjart, Nadezhdina, E. (Elena), Nadezhdina, Elena S, Anjum, R. (Rana), Yulia A. Komarova, Joseph M. Schober, Komarova, Yulia A, Borisy, Gary G., Rana Anjum, Elena S. Nadezhdina, Oana Danciu, Haren, J.A.J. (Jeffrey) van, Anna Akhmanova, Peloquin, John G, Peloquin, John G., Anjum, Rana, Gygi, Steven P., Lee, H.S. (Hahn), Galjart, N.J. (Niels), Schober, Joseph M, Gygi, Steven P, Komarova, Yulia A., Schober, Joseph M., Danciu, Oana, Galjart, Niels, Gygi, S.P. (Steven), Akhmanova, Anna   +43 more
core   +1 more source

PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics

, 2022
Although the immune checkpoint function of PD-L1 has dominated its study, we report that PD-L1 has an unanticipated intrinsic function in promoting the dynamics of persistent cell migration.
Wang, Mengdie, Mercurio, Arthur M., Xiong, Choua   +2 more
core   +1 more source

Characterization of atherosclerotic plaques in blood vessels with low oxygenated blood and blood pressure (Pulmonary trunk): role of growth differentiation factor-15 (GDF-15)

BMC Cardiovascular Disorders, 2021
Background Growth differentiation factor (GDF)-15 is linked to inflammation, cancer, and atherosclerosis. GDF-15 is expressed in most tissues but is extremely induced under pathological conditions. Elevated serum levels are suggested as a risk factor and
G. A. Bonaterra, N. Struck, S. Zuegel, A. Schwarz, L. Mey, H. Schwarzbach, J. Strelau, R. Kinscherf   +7 more
doaj   +1 more source

Simulating cell biology [PDF]

Current Biology, 2006
As with the experimental sciences, the cell simulation field is largely driven by the development of new techniques, and of new tools that implement those techniques. Many techniques under development are working to increase simulation accuracy while reducing the computational burden.
Andrews, Steven S., Arkin, Adam P.
openaire   +2 more sources

Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]

, 2014
Peer ...
Findlay, Amy S., Ouyang, Zhufeng, Zakrewska, Ewa, Kuan, Soh-Leh, Durward, Elaine, Nakamoto, Masaru, Findlay, Amy, Zakrzewska, Ewa, Nakamoto, Chizu, Kuan, Soh Leh, Endo, Takuma   +10 more
core   +1 more source

Spatial regulation of MCAK promotes cell polarization and focal adhesion turnover to drive robust cell migration

, 2021
The asymmetric distribution of microtubule (MT) dynamics in migrating cells is important for cell polarization, yet the underlying regulatory mechanisms remain underexplored.
Hazelbaker, Mark, Moe, Christina, Walczak, Claire E., Zong, Hailing, Ems-McClung, Stephanie C., Hu, Ke   +5 more
core   +1 more source

Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

Stem Cell Research & Therapy, 2019
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation.
Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Margus Pooga, Toivo Maimets   +6 more
doaj   +1 more source

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

Cell Communication and Signaling, 2020
Background Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways.
Małgorzata Maksymowicz, Marta Miączyńska, Magdalena Banach-Orłowska   +2 more
doaj   +1 more source

Cell biology of fat storage [PDF]

, 2016
The worldwide epidemic of obesity and type 2 diabetes has greatly increased interest in the biology and physiology of adipose tissues. Adipose (fat) cells are specialized for the storage of energy in the form of triglycerides, but research in the last ...
Cohen, Paul, Spiegelman, Bruce
core   +1 more source