Results 21 to 30 of about 3,610,600 (306)

The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]

, 2020
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C, Chapman, Hal A, Engler, Anna E, Guo, Minzhe, Herriges, Michael J, Kathiriya, Jaymin J, Katzen, Jeremy, Kotton, Darrell N, Morrisey, Edward E, Rock, Jason R, Snoeck, Hans-Willem, Vunjak-Novakovic, Gordana, Whitsett, Jeffrey A, Windmueller, Rebecca, Ysasi, Alexandra B, Zacharias, William J   +15 more
core   +2 more sources

Clathrin- and dynamin-dependent endocytosis limits canonical NF-κB signaling triggered by lymphotoxin β receptor

Cell Communication and Signaling, 2020
Background Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways.
Małgorzata Maksymowicz, Marta Miączyńska, Magdalena Banach-Orłowska   +2 more
doaj   +1 more source

Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

Malaria Journal, 2021
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson   +8 more
doaj   +1 more source

Human pluripotent stem cell-derived DDX4 and KRT-8 positive cells participate in ovarian follicle-like structure formation

iScience, 2021
Summary: Understanding the mechanisms of human pluripotent stem cells (hPSCs) specification, development and differentiation to gametes are useful for elucidating the causes of infertility and potential treatment. This study aims to examine whether hPSCs
Danny C.W. Yu, Fang-Chun Wu, Chia-Eng Wu, Lu-Ping Chow, Hong-Nerng Ho, Hsin-Fu Chen   +5 more
doaj   +1 more source

Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

Stem Cell Research & Therapy, 2019
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation.
Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Margus Pooga, Toivo Maimets   +6 more
doaj   +1 more source

Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase

iScience, 2023
Summary: The DNA-damage response is a complex signaling network that guards genomic integrity. The microtubule cytoskeleton is involved in the repair of DNA double-strand breaks; however, little is known about which cytoskeleton-related proteins are ...
Arlinda Dullovi, Meryem Ozgencil, Vinothini Rajvee, Wai Yiu Tse, Pedro R. Cutillas, Sarah A. Martin, Zuzana Hořejší   +6 more
doaj   +1 more source

Myoneurin regulates BMP signaling by competing with Ppm1a for Smad binding

iScience, 2022
Summary: A delicate balance of BMP activity is critical for tissue formation and organogenesis. However, the mechanical molecular details in ensuring the proper duration and intensity of BMP signaling have yet to be fully elucidated.
Shuyan Yang, Guozhu Ning, Yiming Hou, Yu Cao, Jin Xu, Jianxin Wu, Ting Zhang, Qiang Wang   +7 more
doaj   +1 more source

Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]

, 2015
A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA, CARBONE, Antonio, DELLA ROCCA, Carlo, DI CARLO, ANGELINA, FAZI, Francesco, PALLESCHI, GIOVANNI, PASTORE, ANTONIO LUIGI, PETROZZA, Vincenzo, PORTA, NATALE   +8 more
core   +2 more sources

Systems cell biology [PDF]

Journal of Cell Biology, 2014
Systems cell biology melds high-throughput experimentation with quantitative analysis and modeling to understand many critical processes that contribute to cellular organization and dynamics. Recently, there have been several advances in technology and in the application of modeling approaches that enable the exploration of the dynamic properties of ...
Mast, Fred D., Ratushny, Alexander V., Aitchison, John D.   +2 more
openaire   +3 more sources

Mechanics rules cell biology

Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology, 2010
Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression ...
Wang James HC, Li Bin
doaj   +1 more source