Results 21 to 30 of about 3,638,096 (304)
Chemoresistance acquisition induces a global shift of expression of aniogenesis-associated genes and increased pro-angogenic activity in neuroblastoma cells [PDF]
, 2009 BACKGROUND: Chemoresistance acquisition may influence cancer cell biology. Here, bioinformatics analysis of gene expression data was used to identify chemoresistance-associated changes in neuroblastoma biology.
Barth, Susanne +10 more
core +6 more sources
eLife, 2013 Experiments in Xenopus embryo extracts reveal that changes in cellular biochemistry cause mitotic spindles to decrease in size over the course of early development.
Daniel Needleman
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006 The transition element molybdenum (Mo) is of essential importance for (nearly) all biological systems as it is required by enzymes catalyzing diverse key reactions in the global carbon, sulfur and nitrogen metabolism. The metal itself is biologically inactive unless it is complexed by a special cofactor.
Mendel, Ralf R., Bittner, Florian
openaire +2 more sources
The cell biology of taste [PDF]
Journal of Cell Biology, 2010 Taste buds are aggregates of 50–100 polarized neuroepithelial cells that detect nutrients and other compounds. Combined analyses of gene expression and cellular function reveal an elegant cellular organization within the taste bud. This review discusses the functional classes of taste cells, their cell biology, and current thinking on how taste ...
Chaudhari, Nirupa, Roper, Stephen D.
openaire +3 more sources
BMC Cardiovascular Disorders, 2021 Background Growth differentiation factor (GDF)-15 is linked to inflammation, cancer, and atherosclerosis. GDF-15 is expressed in most tissues but is extremely induced under pathological conditions. Elevated serum levels are suggested as a risk factor and
G. A. Bonaterra +7 more
doaj +1 more source
Interactive learning in biology with PhotoCD and associated software [PDF]
, 1995 This paper describes the pioneering development of flexible‐learning courseware in the teaching and learning of cell biology using a novel optical disk‐based technology — PhotoCD — and its associated computer software.
Baggott, Linda, Wright, Bruce
core +2 more sources
“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Methods and Protocols, 2019 Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
doaj +1 more source
A human immunodeficiency virus type 1 tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-Mediated inactivation of P-TEFb [PDF]
, 2004 The HEXIM1 protein inhibits the kinase activity of P-TEFb (CDK9/cyclin T) to suppress RNA polymerase II transcriptional elongation in a process that specifically requires the 7SK snRNA, which mediates the interaction of HEXIM1 with P-TEFb.
Yik, JHN（Department of Molecular and Cell Biology, University of California, Berkeley, California 94720） +5 more
core +1 more source
Malaria Journal, 2021 Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy +8 more
doaj +1 more source
ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
iScience, 2021 Summary: DNA double-strand break (DSB) repair by homologous recombination (HR) is essential for ensuring genome stability. Abnormal spindle-like microcephaly-associated (ASPM) gene encodes a spindle protein that is commonly implicated in primary ...
Shibin Xu +5 more
doaj +1 more source