Results 11 to 20 of about 2,064,949 (265)
Cell Biology of the Mitochondrion [PDF]
AbstractMitochondria are best known for harboring pathways involved in ATP synthesis through the tricarboxylic acid cycle and oxidative phosphorylation. Major advances in understanding these roles were made with Caenorhabditiselegans mutants affecting key components of the metabolic pathways.
van der Bliek, Alexander M +2 more
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Contains fulltext : 284072.pdf (Publisher’s version ) (Open Access)
Andrews, Brenda +12 more
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Background Growth differentiation factor (GDF)-15 is linked to inflammation, cancer, and atherosclerosis. GDF-15 is expressed in most tissues but is extremely induced under pathological conditions. Elevated serum levels are suggested as a risk factor and
G. A. Bonaterra +7 more
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The transition element molybdenum (Mo) is of essential importance for (nearly) all biological systems as it is required by enzymes catalyzing diverse key reactions in the global carbon, sulfur and nitrogen metabolism. The metal itself is biologically inactive unless it is complexed by a special cofactor.
Mendel, Ralf R., Bittner, Florian
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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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As with the experimental sciences, the cell simulation field is largely driven by the development of new techniques, and of new tools that implement those techniques. Many techniques under development are working to increase simulation accuracy while reducing the computational burden.
Andrews, Steven S., Arkin, Adam P.
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ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
Summary: DNA double-strand break (DSB) repair by homologous recombination (HR) is essential for ensuring genome stability. Abnormal spindle-like microcephaly-associated (ASPM) gene encodes a spindle protein that is commonly implicated in primary ...
Shibin Xu +5 more
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Summary: Understanding the mechanisms of human pluripotent stem cells (hPSCs) specification, development and differentiation to gametes are useful for elucidating the causes of infertility and potential treatment. This study aims to examine whether hPSCs
Danny C.W. Yu +5 more
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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14
Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation.
Egle-Helene Ervin +6 more
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Background Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways.
Małgorzata Maksymowicz +2 more
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