Results 11 to 20 of about 3,610,600 (306)
A human immunodeficiency virus type 1 tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-Mediated inactivation of P-TEFb [PDF]
, 2004 The HEXIM1 protein inhibits the kinase activity of P-TEFb (CDK9/cyclin T) to suppress RNA polymerase II transcriptional elongation in a process that specifically requires the 7SK snRNA, which mediates the interaction of HEXIM1 with P-TEFb.
Yik, JHN（Department of Molecular and Cell Biology, University of California, Berkeley, California 94720） +5 more
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The developmental cell biology of Trypanosoma brucei [PDF]
, 2005 Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which
Matthews, Keith R
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NaNog: A pluripotency homeobox (master) molecule. [PDF]
, 2015 One of the most intriguing aspects of cell biology is the state of pluripotency, where the cell is capable of self-renewal for as many times as deemed necessary , then at a specified time can differentiate into any type of cell. This fundamental process
Aguib, YE +4 more
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Molecular Biology of the Cell, 2011 How does the nucleus move within the cell? How is the nucleus compartmentalized? How is nuclear size maintained? How is chromatin organized within the nucleus? These are a few of the questions related to nuclear cell biology addressed by our Minisymposium. Dan Starr led off with a description of how nuclei migrate in Caenorhabditis elegans.
Pombo, A., Starr, D.A.
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BMC Cardiovascular Disorders, 2021 Background Growth differentiation factor (GDF)-15 is linked to inflammation, cancer, and atherosclerosis. GDF-15 is expressed in most tissues but is extremely induced under pathological conditions. Elevated serum levels are suggested as a risk factor and
G. A. Bonaterra +7 more
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Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats [PDF]
, 2019 From studies on different species and in cell culture systems, it has been suggested that vitamin D metabolites might affect themetabolism and elimination of xenobiotics.
Hansen, Kathrin +7 more
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Current Biology, 2006 As with the experimental sciences, the cell simulation field is largely driven by the development of new techniques, and of new tools that implement those techniques. Many techniques under development are working to increase simulation accuracy while reducing the computational burden.
Andrews, Steven S., Arkin, Adam P.
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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Methods and Protocols, 2019 Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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ASPM promotes homologous recombination-mediated DNA repair by safeguarding BRCA1 stability
iScience, 2021 Summary: DNA double-strand break (DSB) repair by homologous recombination (HR) is essential for ensuring genome stability. Abnormal spindle-like microcephaly-associated (ASPM) gene encodes a spindle protein that is commonly implicated in primary ...
Shibin Xu +5 more
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Homeostasis as the Mechanism of Evolution. [PDF]
, 2015 Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
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