Results 31 to 40 of about 3,538,937 (352)
Homeostasis as the Mechanism of Evolution. [PDF]
, 2015 Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
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Cell Biology: Scaling and the Emergence of Evolutionary Cell Biology
Current Biology, 2015 A new study investigating the origins of diversity in the structure of the mitotic spindle in nematode embryos, at timescales spanning a few generations to hundreds of millions of years, finds that most features of the spindle evolve via a scaling relationship generated by natural selection acting directly upon embryo size.
Bruce Bowerman, Patrick C. Phillips
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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14
Stem Cell Research & Therapy, 2019 Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation.
Egle-Helene Ervin +6 more
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Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]
, 2009 Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley +108 more
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The cell biology of glycosphingolipids
Seminars in Cell & Developmental Biology, 2004 Glycosphingolipids, a family of heterogeneous lipids with biophysical properties conserved from fungi to mammals, are key components of cellular membranes. Because of their tightly packed backbone, they have the ability to associate with other sphingolipids and cholesterol to form microdomains called lipid rafts, with which a variety of proteins ...
Degroote, S. +2 more
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Reproducibility and cell biology [PDF]
Journal of Cell Biology, 2015 ![Figure][1] © Sidney Harris The New Yorker Collection/The Cartoon Bank Growing concerns about the reproducibility of published research threaten to undermine the scientific enterprise and erode public trust.
Kenneth M. Yamada, Alan Hall
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Global parameter identification of stochastic reaction networks from single trajectories [PDF]
, 2011 We consider the problem of inferring the unknown parameters of a stochastic biochemical network model from a single measured time-course of the concentration of some of the involved species.
A Auger +38 more
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Trakya University Journal of Natural Sciences, 2019 Cancer is becoming the leading cause of death all around the world. To develop better therapeutic options against cancer, we need a thorough understanding of tumor development and dissemination. As our knowledge increases, it becomes apparent that cancer
Serkan İsmail Göktuna +2 more
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The Cell Biology of Heterochromatin
Cells, 2022 A conserved feature of virtually all higher eukaryotes is that the centromeres are embedded in heterochromatin. Here we provide evidence that this tight association between pericentric heterochromatin and the centromere is essential for proper metaphase exit and progression into telophase. Analysis of chromosome rearrangements that separate pericentric
Brandt Warecki, William Sullivan
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Oncogenic microRNAs characterization in clear cell renal cell carcinoma [PDF]
, 2015 A key challenge for the improvement of clear cell renal cell carcinoma (ccRCC) management could derive from a deeper characterization of the biology of these neoplasms that could greatly improve the diagnosis, prognosis and treatment choice. The aim of
BELLISSIMO, TERESA +8 more
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