Results 51 to 60 of about 3,584,225 (304)
Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology. [PDF]
, 2019 High costs and technical limitations of cell sorting and single-cell techniques currently restrict the collection of large-scale, cell-type-specific DNA methylation data.
Barcellos, Lisa F +8 more
core
Premise and peril of Wnt signaling activation through GSK-3β inhibition
iScience, 2022 Summary: Wnt signaling pathways have been extensively studied in the context of several diseases, including cancer, coronary artery disease, and age-related disorders.
Samuel M. Law, Jie J. Zheng
doaj +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Empowering statistical methods for cellular and molecular biologists. [PDF]
, 2019 We provide guidelines for using statistical methods to analyze the types of experiments reported in cellular and molecular biology journals such as Molecular Biology of the Cell.
Pollard, Daniel A +2 more
core
Noise in multiple sclerosis: unwanted and necessary [PDF]
, 2014 As our knowledge about the etiology of multiple sclerosis (MS) increases, deterministic paradigms appear insufficient to describe the pathogenesis of the disease, and the impression is that stochastic phenomena (i.e.
BORDI, Isabella +7 more
core +1 more source
Insights into mucosal associated invariant T cell biology from human inborn errors of immunity [PDF]
, 2022 Lauren J. Howson, Vanessa L. Bryant
openalex +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Heads and Tails: Molecular Imagination and the Lipid Bilayer, 1917–1941 [PDF]
, 2018 Today, the lipid bilayer structure is nearly ubiquitous, taken for granted in even the most rudimentary introductions to cell biology. Yet the image of the lipid bilayer, built out of lipids with heads and tails, went from having obscure origins deep in ...
Liu, Daniel
core
The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future. [PDF]
, 2020 The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex multi-cellular organ that intimately links with the cardiovascular system to accomplish gas exchange.
Basil, Maria C +15 more
core +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source