Results 21 to 30 of about 599,411 (264)

T Cell Microvilli: Sensors or Senders?

Frontiers in Immunology, 2019
Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim, Hye-Ran Kim, Chang-Duk Jun, Chang-Duk Jun   +3 more
doaj   +1 more source

Single-cell analysis reveals melanocytes may promote inflammation in chronic wounds through cathepsin G

Frontiers in Genetics, 2023
During acute wound (AW) healing, a series of proper communications will occur between different epidermal cells at precise temporal stages to restore the integrity of the skin.
Aobuliaximu Yakupu, Aobuliaximu Yakupu, Di Zhang, Di Zhang, Haonan Guan, Haonan Guan, Minfei Jiang, Minfei Jiang, Jiaoyun Dong, Jiaoyun Dong, Yiwen Niu, Yiwen Niu, Jiajun Tang, Jiajun Tang, Yingkai Liu, Yingkai Liu, Xian Ma, Xian Ma, Shuliang Lu, Shuliang Lu   +19 more
doaj   +1 more source

Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation

Frontiers in Immunology
BackgroundOsteosarcoma (OS) is one of the most common primary malignant bone tumors, primarily originating from mesenchymal tissue. It is notorious for its high invasiveness, high disability rate, high mortality rate, and poor prognosis.
Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang   +4 more
doaj   +1 more source

Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses

Journal of Extracellular Vesicles, 2021
Infectious organisms and damage of cells can activate inflammasomes, which mediate tissue inflammation and adaptive immunity. These mechanisms evolved to curb the spread of microbes and to induce repair of the damaged tissue.
Christina F. Budden, Linden J. Gearing, Romina Kaiser, Lena Standke, Paul J. Hertzog, Eicke Latz   +5 more
doaj   +1 more source

The Role of Exosomes in the Pathophysiology of Chronic Rhinosinusitis

Frontiers in Cellular and Infection Microbiology, 2022
Non-invasive biomarker analysis has made repetitive and painless sampling over time possible. Exosomes are being released from a parent cell and their cargo mirrors the cell micromilieu of the parent cell. Therefore, exosomes are promising surrogates for
Sarina K. Mueller
doaj   +1 more source

The role of SASP in ischemic stroke: a deep dive into cellular mechanisms

Frontiers in Neurology
BackgroundThe escalating incidence of ischemic stroke (IS) exerts a heavy toll on global health. Aging, a prominent risk factor, implicates the senescence-associated secretory phenotype (SASP) in IS pathogenesis.
Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang   +3 more
doaj   +1 more source

Roles of the m6A Modification of RNA in the Glioblastoma Microenvironment as Revealed by Single-Cell Analyses

Frontiers in Immunology, 2022
PurposeGlioblastoma multiforme (GBM) is a common and aggressive form of brain tumor. The N6-methyladenosine (m6A) mRNA modification plays multiple roles in many biological processes and disease states.
Feng Yuan, Xiangming Cai, Zixiang Cong, Yingshuai Wang, Yuanming Geng, Yiliyaer Aili, Chaonan Du, Junhao Zhu, Jin Yang, Chao Tang, Aifeng Zhang, Aifeng Zhang, Sheng Zhao, Sheng Zhao, Sheng Zhao, Chiyuan Ma, Chiyuan Ma, Chiyuan Ma, Chiyuan Ma, Chiyuan Ma   +19 more
doaj   +1 more source

Unheard and Under‐Supported: Health‐Related Quality of Life in Children, Adolescents, and Young Adults With Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
Abstract Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy affecting millions of individuals worldwide. The clinical expression and psychosocial burden of SCD vary widely across geographical, cultural, and healthcare system contexts, underscoring the need for setting‐specific approaches to assessment.
Desiré Fantasia, Giulia Reggiani, Elizabeth J. Maran, Maria Elisa Delle Fave, Ilaria Baido, Anna Chiara Frigo, Maria Paola Boaro, Raffaella Colombatti   +7 more
wiley   +1 more source

Intraspecies cell–cell communication in yeast [PDF]

FEMS Yeast Research, 2019
ABSTRACT Although yeasts are unicellular microorganisms that can live independently, they can also communicate with other cells, in order to adapt to the environment. Two yeast species, the budding yeast Saccharomyces cerevisiae and the fission yeast Schizosaccharomyces pombe, engage in various kinds of intraspecies cell–cell ...
Yoko, Yashiroda, Minoru, Yoshida
openaire   +2 more sources

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source