Results 21 to 30 of about 13,173,007 (100)
Comparative analysis of cell–cell communication at single-cell resolution
bioRxiv, 2022 Inference of cell–cell communication from single-cell RNA sequencing data is a powerful technique to uncover intercellular communication pathways, yet existing methods perform this analysis at the level of the cell type or cluster, discarding single-cell-
Aaron J. Wilk +3 more
semanticscholar +1 more source
Endothelial Ion Channels and Cell-Cell Communication in the Microcirculation
Frontiers in Physiology, 2022 Endothelial cells in resistance arteries, arterioles, and capillaries express a diverse array of ion channels that contribute to Cell-Cell communication in the microcirculation.
W. Jackson
semanticscholar +1 more source
Biology, 2020 Innate immunity is continuously revealing multiple and highly conserved host–defence mechanisms. Studies on mammalian immunocytes are showing different communication systems that may play a role in coordinating innate immune responses also in ...
Manon Auguste +3 more
doaj +1 more source
Insights into intercellular receptor-ligand binding kinetics in cell communication
Frontiers in Bioengineering and Biotechnology, 2022 Cell-cell communication is crucial for cells to sense, respond and adapt to environmental cues and stimuli. The intercellular communication process, which involves multiple length scales, is mediated by the specific binding of membrane-anchored receptors
Chenyi An +6 more
doaj +1 more source
Nature Communications, 2022 Spatially resolved transcriptomics provides genetic information in space toward elucidation of the spatial architecture in intact organs and the spatially resolved cell-cell communications mediating tissue homeostasis, development, and disease.
Xin Shao +11 more
semanticscholar +1 more source
Controlling Synthetic Cell-Cell Communication
Frontiers in Molecular Biosciences, 2022 Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic cells,
Jefferson M. Smith +2 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 Cancer can be described as a dynamic disease formed by malignant and stromal cells. The cellular interaction between these components in the tumor microenvironment (TME) dictates the development of the disease and can be mediated by extracellular ...
Nathalia Leal Santos +5 more
doaj +1 more source
Understanding cell‐cell communication and signaling in the colorectal cancer microenvironment
Clinical and Translational Medicine, 2021 Carcinomas are complex heterocellular systems containing epithelial cancer cells, stromal fibroblasts, and multiple immune cell‐types. Cell‐cell communication between these tumor microenvironments (TME) and cells drives cancer progression and influences ...
Shaikha AlMusawi +2 more
semanticscholar +1 more source
Molecular Oncology, 2022 Gliomas cause high mortality around the world. The metabolic pattern of the tumor was previously suggested to be associated with the patient's survival outcome and immune activity. Yet, this relationship in glioma remains unknown.
Hao Zhang +14 more
doaj +1 more source
On the roles of intrinsically disordered proteins and regions in cell communication and signaling
Cell Communication and Signaling, 2021 For proteins, the sequence → structure → function paradigm applies primarily to enzymes, transmembrane proteins, and signaling domains. This paradigm is not universal, but rather, in addition to structured proteins, intrinsically disordered proteins and ...
Sarah E. Bondos, A. Dunker, V. Uversky
semanticscholar +1 more source