Results 31 to 40 of about 595,345 (267)

Controlled Construction of Stable Network Structure Composed of Honeycomb-Shaped Microhydrogels

Life, 2018
Recently, the construction of models for multicellular systems such as tissues has been attracting great interest. These model systems are expected to reproduce a cell communication network and provide insight into complicated functions in living systems.
Masayuki Hayakawa, Satoshi Umeyama, Ken H. Nagai, Hiroaki Onoe, Masahiro Takinoue   +4 more
doaj   +1 more source

Exercise Modifies the Transcriptional Regulatory Features of Monocytes in Alzheimer’s Patients: A Multi-Omics Integration Analysis Based on Single Cell Technology

Frontiers in Aging Neuroscience, 2022
Monocytes have been reported to be important mediators of the protective effect of exercise against the development of Alzheimer’s disease (AD). This study aims explored the mechanism by which monocytes achieve this.
Yisheng Chen, Yaying Sun, Zhiwen Luo, Xiangjun Chen, Yi Wang, Beijie Qi, Jinrong Lin, Wei-Wei Lin, Chenyu Sun, Yifan Zhou, Yifan Zhou, Jiebin Huang, Yuzhen Xu, Jiwu Chen, Shiyi Chen   +14 more
doaj   +1 more source

Single-cell RNA sequencing in diabetic kidney disease: a literature review

Renal Failure
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), and its pathogenesis has not been clarified. Current research suggests that DKD involves multiple cell types and extra-renal factors, and it is particularly important ...
Wei Tan, Jiaoyan Chen, Yunyan Wang, Kui Xiang, Xianqiong Lu, Qiuyu Han, Mingyue Hou, Jurong Yang   +7 more
doaj   +1 more source

Role of extracellular vesicles in cancer: implications in immunotherapeutic resistance

Frontiers in Immunology
Extracellular vesicles (EVs) are lipid membrane-bound vesicles involved in cell-cell communication, particularly in the context of cancer. Immunotherapy, a rapidly evolving field in oncology, is a type of cancer treatment relying on the body’s own immune
Shuai Wang, Zerui Wang, Min Liu, Xiyang Sun   +3 more
doaj   +1 more source

Tumor Necrosis Factor Alpha Signaling and Organogenesis

Frontiers in Cell and Developmental Biology, 2021
Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You, Hui Gu, Zhengwei Yuan, Xuewen Xu, Xuewen Xu   +4 more
doaj   +1 more source

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk

Frontiers in Cell and Developmental Biology, 2021
Calcified aortic valve disease (CAVD), the most common valvular heart disease, lacks pharmaceutical treatment options because its pathogenesis remains unclear.
Qian Zhou, Qian Zhou, Qian Zhou, Hong Cao, Xiaoyi Hang, Xiaoyi Hang, Xiaoyi Hang, Huamin Liang, Huamin Liang, Huamin Liang, Miaomiao Zhu, Miaomiao Zhu, Miaomiao Zhu, Yixian Fan, Yixian Fan, Yixian Fan, Jiawei Shi, Nianguo Dong, Ximiao He, Ximiao He, Ximiao He   +20 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Integration of Single-Cell Transcriptomics Data Reveal Differences in Cell Composition and Communication in Acne

Clinical, Cosmetic and Investigational Dermatology, 2023
Chen-Xi Zhao, Shi-Lei Wang, Hai-Xia Li, Xin Li Department of Cosmetology and Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400021, People’s Republic of ChinaCorrespondence: Xin Li, Department of Cosmetology and Dermatology ...
Zhao CX, Wang SL, Li HX, Li X
doaj  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source