Results 51 to 60 of about 13,173,007 (100)

Force-Mediating Magnetic Nanoparticles to Engineer Neuronal Cell Function

Frontiers in Neuroscience, 2018
Cellular processes like membrane deformation, cell migration, and transport of organelles are sensitive to mechanical forces. Technically, these cellular processes can be manipulated through operating forces at a spatial precision in the range of ...
Trevor J. Gahl, Anja Kunze
doaj   +1 more source

Tumor Necrosis Factor Alpha Signaling and Organogenesis

Frontiers in Cell and Developmental Biology, 2021
Tumor necrosis factor alpha (TNF-α) plays important roles in processes such as immunomodulation, fever, inflammatory response, inhibition of tumor formation, and inhibition of viral replication.
Kai You, Hui Gu, Zhengwei Yuan, Xuewen Xu, Xuewen Xu   +4 more
doaj   +1 more source

Extracellular Vesicles in Trypanosomatids: Host Cell Communication

Frontiers in Cellular and Infection Microbiology, 2020
Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae: Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis and Leishmaniases worldwide.
A. Torrecilhas, R. Soares, S. Schenkman, C. Fernández-Prada, M. Olivier   +4 more
semanticscholar   +1 more source

Exercise Modifies the Transcriptional Regulatory Features of Monocytes in Alzheimer’s Patients: A Multi-Omics Integration Analysis Based on Single Cell Technology

Frontiers in Aging Neuroscience, 2022
Monocytes have been reported to be important mediators of the protective effect of exercise against the development of Alzheimer’s disease (AD). This study aims explored the mechanism by which monocytes achieve this.
Yisheng Chen, Yaying Sun, Zhiwen Luo, Xiangjun Chen, Yi Wang, Beijie Qi, Jinrong Lin, Wei-Wei Lin, Chenyu Sun, Yifan Zhou, Yifan Zhou, Jiebin Huang, Yuzhen Xu, Jiwu Chen, Shiyi Chen   +14 more
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Small GTPases orchestrate cell-cell communication during collective cell movement

Small GTPases, 2020
Collective cell migration is a critical mechanism involved in cell movement during various physiological and pathological processes such as angiogenesis and metastasis formation.
Anne Combedazou, S. Gayral, N. Colombié, A. Fougerat, M. Laffargue, D. Ramel   +5 more
semanticscholar   +1 more source

Single-cell mechanistic studies of radiation-mediated bystander effects

Frontiers in Immunology, 2022
Ionizing radiation (IR) has been widely used in the diagnosis and treatment of clinical diseases, with radiation therapy (RT) being particularly rapid, but it can induce “bystander effects” that lead to biological responses in non-target cells after ...
Xueqiong Han, Yixuan Chen, Nan Zhang, Chengyu Huang, Guangyao He, Ting Li, Mengxin Wei, Qiong Song, Shaowen Mo, Yufeng Lv   +9 more
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miRNAs as Influencers of Cell–Cell Communication in Tumor Microenvironment

Cells, 2020
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at the posttranscriptional level, inducing the degradation of the target mRNA or translational repression.
Ilaria Conti, G. Varano, C. Simioni, I. Laface, D. Milani, E. Rimondi, L. Neri   +6 more
semanticscholar   +1 more source

Integrating cell interaction with transcription factors to obtain a robust gene panel for prognostic prediction and therapies in cholangiocarcinoma

Frontiers in Genetics, 2022
Objective: The efficacy of immunotherapy for cholangiocarcinoma (CCA) is blocked by a high degree of tumor heterogeneity. Cell communication contributes to heterogeneity in the tumor microenvironment.
Tingjie Wang, Chuanrui Xu, Dan Xu, Xiaofei Yang, Xiaofei Yang, Xiaofei Yang, Yaxin Liu, Xiujuan Li, Zihang Li, Ningxin Dang, Yi Lv, Zhijing Zhang, Lei Li, Kai Ye, Kai Ye, Kai Ye, Kai Ye, Kai Ye, Kai Ye   +18 more
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In-depth mining of single-cell transcriptome reveals the key immune-regulated loops in age-related macular degeneration

Frontiers in Molecular Neuroscience, 2023
IntroductionAge-related macular degeneration (AMD), an ever-increasing ocular disease, has become one of the leading causes of irreversible blindness. Recent advances in single-cell genomics are improving our understanding of the molecular mechanisms of ...
Wencan Wang, Wencan Wang, Wencan Wang, Peng Lin, Peng Lin, Peng Lin, Siyu Wang, Siyu Wang, Siyu Wang, Guosi Zhang, Guosi Zhang, Guosi Zhang, Chong Chen, Chong Chen, Chong Chen, Xiaoyan Lu, Xiaoyan Lu, Xiaoyan Lu, Youyuan Zhuang, Youyuan Zhuang, Youyuan Zhuang, Jianzhong Su, Jianzhong Su, Jianzhong Su, Jianzhong Su, Hong Wang, Hong Wang, Hong Wang, Hong Wang, Liangde Xu, Liangde Xu, Liangde Xu, Liangde Xu   +32 more
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Exosome-Based Cell-Cell Communication in the Tumor Microenvironment

Front. Cell Dev. Biol., 2018
Tumors are not isolated entities, but complex systemic networks involving cell-cell communication between transformed and non-transformed cells. The milieu created by tumor-associated cells may either support or halt tumor progression.
Joana Maia, S. Caja, Maria Carolina Strano Moraes, Nuno Couto, B. Costa-Silva   +4 more
semanticscholar   +1 more source